Reactome | KCNH5 [plasma membrane]

KCNH5 [plasma membrane]

Stable Identifier

R-HSA-1296099

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Potassium voltage-gated channel subfamily H member 5, KCNH5_HUMAN

Locations in the PathwayBrowser

Expand all

Neuronal System (Homo sapiens)

- Potassium Channels (Homo sapiens)
  - Voltage gated Potassium channels (Homo sapiens)
    - Activation of voltage gated Potassium channels (Homo sapiens)
      - Octamer of Voltage gated K+ channels [plasma membrane] (Homo sapiens)
        
        Voltage gated potassium channel subunits Kv1-12 [plasma membrane] (Homo sapiens)
        
        Kv10 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)
        
        KCNH5 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q8NCM2 KCNH5

Gene Names

KCNH5, EAG2

Chain

chain:1-988

Reference Genes

BioGPS Gene:27133 KCNH5

COSMIC (genes):KCNH5 KCNH5

CTD Gene:27133 KCNH5

dbSNP Gene:27133 KCNH5

ENSEMBL:ENSG00000140015 KCNH5

HGNC:6254 KCNH5

KEGG Gene (Homo sapiens):27133 KCNH5

Monarch:27133 KCNH5

NCBI Gene:27133 KCNH5

OMIM:605716 KCNH5

UCSC:Q8NCM2 KCNH5

Reference Transcript

Other Identifiers

0001770332

0001770438

11740623_a_at

11741820_a_at

11742221_a_at

11749766_a_at

11759356_at

1555074_a_at

1555304_a_at

16793692

242502_at

27133

3567880

3567881

3567882

3567883

3567884

3567885

3567886

3567887

3567888

3567889

3567890

3567894

3567895

3567896

3567904

3567906

3567907

3567911

3567929

3567930

3567931

3567933

3567934

3567935

3567937

3567941

3567944

3567945

3567946

3567952

3567953

47008_at

7979529

A_23_P25849

A_24_P99145

A_32_P168561

A_33_P3344334

A_33_P3344339

GO:0000278

GO:0003674

GO:0005216

GO:0005244

GO:0005249

GO:0005267

GO:0005516

GO:0005575

GO:0005886

GO:0005887

GO:0006810

GO:0006811

GO:0006813

GO:0007049

GO:0008150

GO:0009986

GO:0010389

GO:0016020

GO:0016021

GO:0022857

GO:0034765

GO:0042391

GO:0044325

GO:0044877

GO:0055085

GO:0071805

HMNXSV003032918

Hs.27043.0.A1_3p_at

Hs2.27043.3.S1_3p_s_at

ILMN_1700199

ILMN_1729963

PH_hs_0002396

TC14001202.hg

Participates

as a member of

Kv10 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)

Inferred To

eag [plasma membrane] (Drosophila melanogaster)

KCNH5 [plasma membrane] (Bos taurus)

KCNH5 [plasma membrane] (Canis familiaris)

KCNH5 [plasma membrane] (Gallus gallus)

KCNH5 [plasma membrane] (Sus scrofa)

Kcnh5 [plasma membrane] (Mus musculus)

Kcnh5 [plasma membrane] (Rattus norvegicus)

kcnh5 [plasma membrane] (Xenopus tropicalis)

kcnh5a [plasma membrane] (Danio rerio)

Cross References

RefSeq

NP_758963.1, NP_647479.2

Guide to Pharmacology - Targets

571

OpenTargets

ENSG00000140015

GeneCards

Q8NCM2

HPA

ENSG00000140015-KCNH5

Ensembl

ENSG00000140015, ENST00000394968, ENST00000420622, ENSP00000378419, ENSP00000321427, ENST00000322893, ENSP00000395439

PRO

Q8NCM2

Pharos - Targets

Q8NCM2

GlyGen

Q8NCM2

Orphanet

24637

HMDB Protein

HMDBP08145