Classical Kir channels

Stable Identifier
R-HSA-1296053
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this pathway in the Pathway Browser

Classical Kir channels are inwardly rectifying K+ channels with strong inwardly rectifying currents that contribute to highly negative resting membrane potential, prolonged action potential plateau and rapid repolarization in the final stage of action potential. Classical Kir channels are found in various cells such as cardiac myocytes, purkinje fibers, atrial and ventricular tissues. Rectification is caused by intracellular Mg2+ ions and polyamines.

Literature References
PubMed ID Title Journal Year
10599834 Inward rectifier potassium channel Kir 2.3 is inhibited by internal sulfhydryl modification

Radeke, CM, Conti, LR, Vandenberg, CA

Neuroreport 1999
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created
Cite Us!