Activation of Ca2+ activated Potassium channels with Intermediate conductance

Stable Identifier
R-HSA-1296035
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane, cytosol, extracellular region
ReviewStatus
5/5
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Activation of Ca2+ activated Potassium channels with Intermediate conductance
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Intermediate conductance K+ channels are restricted to non neuronal tissues like epithelia, blood cells and are activated by intracellular Ca2+ ion concentration. Activation of Ca2+ activated K+ channels with intermediate conductance leads to K+ efflux in to the extracellular space.

Literature References
PubMed ID Title Journal Year
19074509 Openers of SKCa and IKCa channels enhance agonist-evoked endothelial nitric oxide synthesis and arteriolar vasodilation

Hill, MA, Ella, S, Braun, AP, Sheng, JZ, Davis, MJ

FASEB J 2009
Participants
Input
Output
Participates
as an event of
Catalyst Activity

potassium channel activity of KCNN4 [plasma membrane]

Physical Entity
KCNN4 [plasma membrane] (Homo sapiens)
Activity
potassium channel activity (GO:0005267)
Orthologous Events
Activation of Ca2+ activated Potassium channels with Intermediate conductance (Caenorhabditis elegans)
Activation of Ca2+ activated Potassium channels with Intermediate conductance (Canis familiaris)
Activation of Ca2+ activated Potassium channels with Intermediate conductance (Danio rerio)
Activation of Ca2+ activated Potassium channels with Intermediate conductance (Dictyostelium discoideum)
Activation of Ca2+ activated Potassium channels with Intermediate conductance (Drosophila melanogaster)
Activation of Ca2+ activated Potassium channels with Intermediate conductance (Mus musculus)
Activation of Ca2+ activated Potassium channels with Intermediate conductance (Rattus norvegicus)
Activation of Ca2+ activated Potassium channels with Intermediate conductance (Sus scrofa)
Activation of Ca2+ activated Potassium channels with Intermediate conductance (Xenopus tropicalis)
Cross References
Rhea
Authored
Mahajan, SS  (2011-05-19)
Reviewed
Jassal, B  (2010-09-23)
Created
Mahajan, SS  (2011-05-19)
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