Reactome | CNDP2 [cytosol]

CNDP2 [cytosol]

Stable Identifier

R-HSA-1258410

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Cytosolic non-specific dipeptidase, CNDP2_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism (Homo sapiens)

- Biological oxidations (Homo sapiens)
  - Phase II - Conjugation of compounds (Homo sapiens)
    - Glutathione conjugation (Homo sapiens)
      - Glutathione synthesis and recycling (Homo sapiens)
        
        CNDP2:2Mn2+ dimer hydrolyses CysGly (Homo sapiens)
        
        CNDP2:2Mn2+ dimer [cytosol] (Homo sapiens)
        
        CNDP2 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q96KP4 CNDP2

Gene Names

CNDP2, CN2, CPGL, HEL-S-13, PEPA

Chain

initiator methionine:, chain:2-475

Reference Genes

BioGPS Gene:55748 CNDP2

COSMIC (genes):CNDP2 CNDP2

CTD Gene:55748 CNDP2

dbSNP Gene:55748 CNDP2

ENSEMBL:ENSG00000133313 CNDP2

ENSEMBL_homo_sapiens_GENE:ENSG00000133313.15 CNDP2

HGNC:24437 CNDP2

KEGG Gene (Homo sapiens):55748 CNDP2

Monarch:55748 CNDP2

NCBI Gene:55748 CNDP2

OMIM:169800 CNDP2

UCSC:Q96KP4 CNDP2

Reference Transcript

Other Identifiers

11715954_a_at

11745841_a_at

11745842_s_at

11756322_x_at

16853071

217752_PM_s_at

217752_s_at

230950_PM_at

230950_at

3793771

3793772

3793780

3793781

3793782

3793783

3793785

3793791

3793792

3793799

3793800

3793803

3793805

3793806

3793808

3793809

3793813

3793815

3793816

3793817

3793818

3793819

3793820

3793824

3793826

55748

57658_at

78775_at

8021727

90104_at

A_23_P89812

A_24_P151084

GE504326

GE88846

GO:0003824

GO:0004180

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006508

GO:0008233

GO:0008237

GO:0016787

GO:0016805

GO:0043226

GO:0046872

GO:0070062

GO:0070573

GO:0103046

GO:0140096

HMNXSV003023361

HMNXSV003057222

Hs.12758.0.A1_3p_at

ILMN_1726769

PH_hs_0022656

TC18000248.hg

g8922698_3p_a_at

Participates

as a component of

CNDP2:2Mn2+ dimer [cytosol] (Homo sapiens)

Inferred To

CNDP2 [cytosol] (Bos taurus)

CNDP2 [cytosol] (Caenorhabditis elegans)

CNDP2 [cytosol] (Canis familiaris)

CNDP2 [cytosol] (Danio rerio)

CNDP2 [cytosol] (Dictyostelium discoideum)

CNDP2 [cytosol] (Drosophila melanogaster)

CNDP2 [cytosol] (Gallus gallus)

CNDP2 [cytosol] (Mus musculus)

CNDP2 [cytosol] (Rattus norvegicus)

CNDP2 [cytosol] (Saccharomyces cerevisiae)

CNDP2 [cytosol] (Schizosaccharomyces pombe)

CNDP2 [cytosol] (Sus scrofa)

CNDP2 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

XP_006722566.1, NP_001161971.1, XP_005266785.1, XP_011524373.1, NP_060705.2, XP_011524374.1

Guide to Pharmacology - Targets

1604

OpenTargets

ENSG00000133313

HPA

ENSG00000133313-CNDP2

GeneCards

Q96KP4

Ensembl

ENSP00000325756, ENSP00000325548, ENSP00000462311, ENSG00000133313, ENST00000324301, ENST00000324262, ENST00000579847

PRO

Q96KP4

Pharos - Targets

Q96KP4

HMDB Protein

HMDBP14079

PDB

4RUH

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.527	4