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What is Reactome ?
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ESR1 dimer:ESTG [nucleoplasm]
Stable Identifier
R-HSA-1254381
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX1 (Homo sapiens)
RUNX1 regulates estrogen receptor mediated transcription (Homo sapiens)
AXIN1 gene expression is inhibited by ESR1 and stimulated by RUNX1 (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:estrogen:AXIN1 gene [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:AXIN1 gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1 binds the AXIN1 gene (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:estrogen:AXIN1 gene [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
GPAM gene expression is stimulated by RUNX1 and ESR1 (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:GPAM gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
KCTD6 gene expression is stimulated by RUNX1 and ESR1 (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:KCTD6 gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1 and ESR1 bind the AXIN1 gene (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:AXIN1 gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1 and ESR1 bind the GPAM gene enhancer (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:GPAM gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1 and ESR1 bind the KCTD6 gene enhancer (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:KCTD6 gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1 binds ESR1 (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1 regulates transcription of genes involved in WNT signaling (Homo sapiens)
AXIN1 gene expression is inhibited by ESR1 and stimulated by RUNX1 (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:estrogen:AXIN1 gene [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:AXIN1 gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1 and ESR1 bind the AXIN1 gene (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:AXIN1 gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Transcriptional regulation by RUNX2 (Homo sapiens)
Regulation of RUNX2 expression and activity (Homo sapiens)
Activated ESR1 binds the RUNX2 gene promoter (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:estrogen:RUNX2 gene [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX2 gene expression from proximal (P2) promoter is stimulated by ESR1:estrogen, ESRRA:PPARG1CA, TWIST1 and RUNX2-P2, and inhibited by ESRRA:PPARG1CB and DEXA:NR3C1 (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:estrogen:RUNX2 gene [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
ESR dimerizes (Homo sapiens)
ESR multimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Estrogen-dependent gene expression (Homo sapiens)
AXIN1 gene expression is inhibited by ESR1 and stimulated by RUNX1 (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:estrogen:AXIN1 gene [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:AXIN1 gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Binding of AP1 transcriptional activator complexes to CCND1 promoter (Homo sapiens)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3:ESTG:ESR1 dimer:JUN:ATF2:POUF21:ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] (Homo sapiens)
ESTG:ESR1 dimer:ATF2:JUN [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESTG:ESR1 dimer:ATF2:JUN [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
CXCL12 gene expression is stimulated by ERBB4s80:ESR1:estrogen (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen:CXCL12 gene [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
EP300 is recruited to MYC and BCL2 genes (Homo sapiens)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
MYC gene, BCL2 gene:HIST1H2AC nuclesome:ESR1:ESTG:EP300 [nucleoplasm] (Homo sapiens)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80 forms a complex with estrogen receptor ESR1 (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1 binds CXCL12 gene promoter (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen:CXCL12 gene [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1 binds PGR gene promoter (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen:PGR gene [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1 binds the AXIN1 gene (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:estrogen:AXIN1 gene [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:ESTG and EP300 are recruited to TFF3 promoter (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
TFF3 gene:FOXA1:GATA3:ESR1:ESTG:EP300 [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:ESTG bind the EBAG9 5' region (Homo sapiens)
EBAG9 gene:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:ESTG binds CXXC5 gene (Homo sapiens)
CXXC5 gene:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:ESTG binds to proximal and distal regions of the CTSD promoter (Homo sapiens)
CTSD gene:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:ESTG, JUND:FOSB and Cohesin Complex bind distal enhancer elements in MYC gene promoter (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
MYC gene:ESR1:ESTG:JUND:FOSB:Cohesin Complex [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Homo sapiens)
ESR1:ESTG:P-TEFb [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Homo sapiens)
ESR1:ESTG:P-TEFb [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators (Homo sapiens)
ESR1:ER:PGR:P4 [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:ESTG:PGR:P4:FOXA1:GATA3:TLE3:NRIP:EP300 [nucleoplasm] (Homo sapiens)
ESR1:ER:PGR:P4 [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Estrogen-responsive BCL2 gene expression (Homo sapiens)
BLC2 gene:HIST1H2AC nuclesome:ESR1:ESTG:EP300 [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Estrogen-responsive CCND1 gene expression (Homo sapiens)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3:ESTG:ESR1 dimer:JUN:ATF2:POUF21:ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] (Homo sapiens)
ESTG:ESR1 dimer:ATF2:JUN [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
CCND1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Estrogen-responsive CTSD expression (Homo sapiens)
CTSD gene:ESR1:ESTG:SP1:USF1:USF2:NCOA:EP300:MED1 [nucleoplasm] (Homo sapiens)
CTSD gene:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Estrogen-responsive CXXC5 gene expresion (Homo sapiens)
CXXC5 gene:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Estrogen-responsive EBAG9 gene expression (Homo sapiens)
EBAG9 gene:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Estrogen-responsive GREB1 gene transcription (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
GREB1 gene:nucleosome:ESR1:ESTG:ZNF217:NCOA3:NR5A2 [nucleoplasm] (Homo sapiens)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Estrogen-responsive KDM4B gene expression (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
KDM4B gene:nucleoplasm:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Estrogen-responsive MYB gene expression (Homo sapiens)
ESR1:ESTG:P-TEFb [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
MYB gene:hyperphosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Homo sapiens)
ESR1:ESTG:P-TEFb [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Estrogen-responsive MYC gene expression (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
MYC gene:ESR1:ESTG:JUND:FOSB:Cohesin Complex [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
MYC gene:HIST1H2AC nucleosome:ESR1:ESTG:EP300:NCOA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
MYC gene:nucleoplasm:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Estrogen-responsive TFF3 gene expression (Homo sapiens)
FOXA1:GATA3:ESR1:ESTG:EP300 [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
TFF3 gene:FOXA1:GATA3:ESR1:ESTG:EP300 [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
GPAM gene expression is stimulated by RUNX1 and ESR1 (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:GPAM gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
GREB1 binds ESR1:ESTG and co-activators (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
GREB1:ESR1:ESTG:EP300:CREBBP [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
HATs and coactivators are recruited to the CTSD gene (Homo sapiens)
CTSD gene:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
CTSD gene:ESR1:ESTG:SP1:USF1:USF2:NCOA:EP300:MED1 [nucleoplasm] (Homo sapiens)
CTSD gene:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
KCTD6 gene expression is stimulated by RUNX1 and ESR1 (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:KCTD6 gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Homo sapiens)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Homo sapiens)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
KDM1A is recruited to MYC and BCL2 genes (Homo sapiens)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Homo sapiens)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Homo sapiens)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
KDM4B-regulated genes:nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
NR5A2, ZNF217 and NCOA3 bind GREB1 promoter (Homo sapiens)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
GREB1 gene:nucleosome:ESR1:ESTG:ZNF217:NCOA3:NR5A2 [nucleoplasm] (Homo sapiens)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
PGR gene expression is stimulated by ERBB4s80:ESR1:estrogen (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen:PGR gene [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1:ER:PGR:P4 [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1 and ESR1 bind the AXIN1 gene (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:AXIN1 gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1 and ESR1 bind the GPAM gene enhancer (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:GPAM gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1 and ESR1 bind the KCTD6 gene enhancer (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:KCTD6 gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1 binds ESR1 (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Homo sapiens)
MYB gene:hyperphosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Homo sapiens)
ESR1:ESTG:P-TEFb [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Homo sapiens)
ESR1:ESTG:P-TEFb [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by ERBB4 (Homo sapiens)
Nuclear signaling by ERBB4 (Homo sapiens)
CXCL12 gene expression is stimulated by ERBB4s80:ESR1:estrogen (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen:CXCL12 gene [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4 gene expression is stimulated by ERBB4s80:ESR1 (Homo sapiens)
ERBB4s80:ESR1:estrogen:ERBB4 gene [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80 forms a complex with estrogen receptor ESR1 (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1 binds CXCL12 gene promoter (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen:CXCL12 gene [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1 binds ERBB4 gene promoter (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen:ERBB4 gene [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1 binds PGR gene promoter (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen:PGR gene [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
PGR gene expression is stimulated by ERBB4s80:ESR1:estrogen (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen:PGR gene [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:ESTG [nucleoplasm] (Homo sapiens)
Participants
components
ESR1 homodimer [nucleoplasm]
(Homo sapiens)
x 2
ESTG [nucleoplasm]
Participates
as a component of
KDM4B gene:nucleoplasm:ESR1:ESTG [nucleoplasm] (Homo sapiens)
GREB1:ESR1:ESTG:EP300:CREBBP [nucleoplasm] (Homo sapiens)
BLC2 gene:HIST1H2AC nuclesome:ESR1:ESTG:EP300 [nucleoplasm] (Homo sapiens)
CTSD gene:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESR1:ER:PGR:P4 [nucleoplasm] (Homo sapiens)
CXXC5 gene:ESR1:ESTG [nucleoplasm] (Homo sapiens)
KDM4B-regulated genes:nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Homo sapiens)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
CCND1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
ESTG:ESR1 dimer:ATF2:JUN [nucleoplasm] (Homo sapiens)
ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] (Homo sapiens)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Homo sapiens)
ESR1:estrogen:RUNX2 gene [nucleoplasm] (Homo sapiens)
ESR1:estrogen:AXIN1 gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen [nucleoplasm] (Homo sapiens)
EBAG9 gene:ESR1:ESTG [nucleoplasm] (Homo sapiens)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Homo sapiens)
FOXA1:GATA3:ESR1:ESTG:EP300 [nucleoplasm] (Homo sapiens)
TFF3 gene:FOXA1:GATA3:ESR1:ESTG:EP300 [nucleoplasm] (Homo sapiens)
ESR1:ESTG:P-TEFb [nucleoplasm] (Homo sapiens)
MYC gene:ESR1:ESTG:JUND:FOSB:Cohesin Complex [nucleoplasm] (Homo sapiens)
MYC gene:nucleoplasm:ESR1:ESTG [nucleoplasm] (Homo sapiens)
MYC gene:HIST1H2AC nucleosome:ESR1:ESTG:EP300:NCOA3 [nucleoplasm] (Homo sapiens)
as an input of
GREB1 binds ESR1:ESTG and co-activators (Homo sapiens)
ESR1:ESTG binds to proximal and distal regions of the CTSD promoter (Homo sapiens)
Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG (Homo sapiens)
ESR1:ESTG binds CXXC5 gene (Homo sapiens)
ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Homo sapiens)
ERBB4s80 forms a complex with estrogen receptor ESR1 (Homo sapiens)
Activated ESR1 binds the RUNX2 gene promoter (Homo sapiens)
ESR1 binds the AXIN1 gene (Homo sapiens)
RUNX1 binds ESR1 (Homo sapiens)
ESR1:ESTG bind the EBAG9 5' region (Homo sapiens)
Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Homo sapiens)
ESR1:ESTG and EP300 are recruited to TFF3 promoter (Homo sapiens)
ESR1:ESTG, JUND:FOSB and Cohesin Complex bind distal enhancer elements in MYC gene promoter (Homo sapiens)
as a member of
ESR multimer:ESTG [nucleoplasm] (Homo sapiens)
Inferred To
ESR1 dimer:ESTG [nucleoplasm]
(Bos taurus)
ESR1 dimer:ESTG [nucleoplasm]
(Caenorhabditis elegans)
ESR1 dimer:ESTG [nucleoplasm]
(Canis familiaris)
ESR1 dimer:ESTG [nucleoplasm]
(Danio rerio)
ESR1 dimer:ESTG [nucleoplasm]
(Dictyostelium discoideum)
ESR1 dimer:ESTG [nucleoplasm]
(Drosophila melanogaster)
ESR1 dimer:ESTG [nucleoplasm]
(Gallus gallus)
ESR1 dimer:ESTG [nucleoplasm]
(Mus musculus)
ESR1 dimer:ESTG [nucleoplasm]
(Rattus norvegicus)
ESR1 dimer:ESTG [nucleoplasm]
(Saccharomyces cerevisiae)
ESR1 dimer:ESTG [nucleoplasm]
(Schizosaccharomyces pombe)
ESR1 dimer:ESTG [nucleoplasm]
(Sus scrofa)
ESR1 dimer:ESTG [nucleoplasm]
(Xenopus tropicalis)
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