Reactome | GFAP gene expression is inhibited by ERBB4:TAB2:NCOR1

GFAP gene expression is inhibited by ERBB4:TAB2:NCOR1

Stable Identifier

R-HSA-1253321

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

nucleoplasm

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GFAP gene expression is inhibited by ERBB4:TAB2:NCOR1

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Transcription of the GFAP gene, involved in astrocyte differentiation, is inhibited by binding of the ERBB4s80:TAB2:NCOR1 complex to the GFAP promoter (Sardi et al. 2006).

Literature References

PubMed ID	Title	Journal	Year
17018285	Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain Sardi, SP, Murtie, J, Koirala, S, Patten, BA, Corfas, G	Cell	2006