GFAP gene expression is inhibited by ERBB4:TAB2:NCOR1

Stable Identifier
R-HSA-1253321
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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GFAP gene expression is inhibited by ERBB4:TAB2:NCOR1
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Transcription of the GFAP gene, involved in astrocyte differentiation, is inhibited by binding of the ERBB4s80:TAB2:NCOR1 complex to the GFAP promoter (Sardi et al. 2006).

Literature References
PubMed ID Title Journal Year
17018285 Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain

Patten, BA, Corfas, G, Koirala, S, Murtie, J, Sardi, SP

Cell 2006
Participants
Input
Output
Participates
as an event of
This event is regulated
Negatively by
Regulator
ERBB4s80:TAB2:NCOR1:GFAP gene [nucleoplasm] (Homo sapiens)
Active Unit
ERBB4s80:TAB2:NCOR1 [nucleoplasm]
Authored
Orlic-Milacic, M  (2011-11-04)
Stern, DF  (2019-02-21)
Reviewed
Zeng, F  (2011-11-11)
Harris, RC  (2011-11-11)
Earp HS, 3rd  (2012-02-20)
Misior, AM  (2012-02-20)
Created
Orlic-Milacic, M  (2011-04-28)
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