Reactome | TIMM17B [mitochondrial inner membrane]

TIMM17B [mitochondrial inner membrane]

Stable Identifier

R-HSA-1252138

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Mitochondrial import inner membrane translocase subunit Tim17-B, TI17B_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O60830 TIMM17B

Gene Names

TIMM17B, TIM17B, JM3

Chain

chain:1-172

Reference Genes

BioGPS Gene:10245 TIMM17B

COSMIC (genes):TIMM17B TIMM17B

CTD Gene:10245 TIMM17B

dbSNP Gene:10245 TIMM17B

ENSEMBL:ENSG00000126768 TIMM17B

HGNC:17310 TIMM17B

KEGG Gene (Homo sapiens):10245 TIMM17B

Monarch:10245 TIMM17B

NCBI Gene:10245 TIMM17B

OMIM:300249 TIMM17B

UCSC:O60830 TIMM17B

Reference Transcript

Other Identifiers

0000430465

10245

11720938_a_at

17110639

203342_at

33713_at

4007570

4007571

4007572

4007574

4007575

4007577

4007578

4007581

4007583

4007584

4007585

8172453

A_23_P33886

A_33_P3380742

GE81566

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005739

GO:0005743

GO:0005744

GO:0006605

GO:0006626

GO:0006810

GO:0006886

GO:0007005

GO:0008150

GO:0015031

GO:0015450

GO:0016020

GO:0016021

GO:0022857

GO:0030150

GO:0031305

GO:0032991

GO:0043226

GO:0055085

ILMN_1813260

TC0X001018.hg

g5032180_3p_at

Participant Of

hasCandidate

Proteins Chaperoned by TIMM9:TIMM10 [mitochondrial inner membrane]

hasMember

TIMM17 [mitochondrial inner membrane]

Other forms of this molecule

TIMM17B [mitochondrial intermembrane space]

Inferred To

timm-17B.1 [mitochondrial inner membrane] (Caenorhabditis elegans)

timm17b [mitochondrial inner membrane] (Danio rerio)

Tim17b [mitochondrial inner membrane] (Drosophila melanogaster)

SLC35A2 [mitochondrial inner membrane] (Canis familiaris)

Cross References

RefSeq

NP_005825.1, NP_001161419.1

OpenTargets

ENSG00000126768

GeneCards

O60830

HPA

ENSG00000126768-TIMM17B

Ensembl

ENSG00000126768, ENST00000396779, ENST00000376582, ENSP00000477073, ENST00000465150, ENSP00000365766, ENSP00000379999

PRO

O60830

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06396 GSN	7	GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(200-270) [extracellular region] (R-HSA-976940) GSN [extracellular region] (R-HSA-6806510) GSN [secretory granule lumen] (R-HSA-6801486) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:Q14957 GRIN2C	3	p-Y-GRIN2C [plasma membrane] (R-HSA-9612189) GRIN2C [plasma membrane] (R-HSA-419560) GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761)	0.556	3
UniProt:P00488 F13A1	4	factor XIII A chain [extracellular region] (R-HSA-140600) factor XIIIa A chain [extracellular region] (R-HSA-140788) factor XIII A chain activation peptide [extracellular region] (R-HSA-140790) F13A1(1-731) [platelet alpha granule lumen] (R-HSA-349759)	0.556	3
UniProt:Q13153 PAK1	6	p-S144-PAK1 [cytosol] (R-HSA-451339) Active PAK1 [cytosol] (R-HSA-8964622) PAK1 [plasma membrane] (R-HSA-3928409) p-S144,T423-PAK1 [plasma membrane] (R-HSA-3928472) PAK1 [cytosol] (R-HSA-162629) p-S144,T423-PAK1 [cytosol] (R-HSA-399819)	0.556	3
UniProt:P04792 HSPB1	3	p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) HSPB1 [cytosol] (R-HSA-450563) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.556	3
UniProt:O76024 WFS1	3	p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3