Reactome | TIMM17B [mitochondrial inner membrane]

TIMM17B [mitochondrial inner membrane]

Stable Identifier

R-HSA-1252138

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Mitochondrial import inner membrane translocase subunit Tim17-B, TI17B_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O60830 TIMM17B

Gene Names

TIMM17B, TIM17B, JM3

Chain

chain:1-172

Reference Genes

BioGPS Gene:10245 TIMM17B

COSMIC (genes):TIMM17B TIMM17B

CTD Gene:10245 TIMM17B

dbSNP Gene:10245 TIMM17B

ENSEMBL:ENSG00000126768 TIMM17B

ENSEMBL:ENSG00000126768.13 TIMM17B

HGNC:17310 TIMM17B

KEGG Gene (Homo sapiens):10245 TIMM17B

Monarch:10245 TIMM17B

NCBI Gene:10245 TIMM17B

OMIM:300249 TIMM17B

UCSC:O60830 TIMM17B

Reference Transcript

Other Identifiers

10245

11720938_a_at

17110639

203342_PM_at

203342_at

33713_at

4007570

4007571

4007572

4007574

4007575

4007577

4007578

4007581

4007583

4007584

4007585

8172453

A_23_P33886

A_33_P3380742

GE81566

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0005744

GO:0006626

GO:0006886

GO:0007005

GO:0008320

GO:0015031

GO:0016020

GO:0030150

GO:0043226

GO:0055085

HMNXSV003011882

ILMN_1813260

TC0X001018.hg

g5032180_3p_at

Participates

as a candidate of

Proteins Chaperoned by TIMM9:TIMM10 [mitochondrial inner membrane] (Homo sapiens)

as a member of

TIMM17 [mitochondrial inner membrane] (Homo sapiens)

Other forms of this molecule

TIMM17B [mitochondrial intermembrane space]

Inferred To

timm-17B.1 [mitochondrial inner membrane] (Caenorhabditis elegans)

TIM17 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

tim17 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

timm17b [mitochondrial inner membrane] (Xenopus tropicalis)

Tim17b [mitochondrial inner membrane] (Drosophila melanogaster)

timm17 [mitochondrial inner membrane] (Dictyostelium discoideum)

si:ch211-163b2.6 [mitochondrial inner membrane] (Danio rerio)

TIMM17B [mitochondrial inner membrane] (Bos taurus)

TIMM17B [mitochondrial inner membrane] (Plasmodium falciparum)

TIMM17B [mitochondrial inner membrane] (Sus scrofa)

Cross References

RefSeq

NP_001161419.1, NP_005825.1

OpenTargets

ENSG00000126768

HPA

ENSG00000126768-TIMM17B

GeneCards

O60830

Ensembl

ENSP00000477073, ENST00000376582, ENSG00000126768, ENST00000396779, ENST00000696123, ENSP00000379999, ENSP00000365766, ENST00000465150, ENSP00000512416

PRO

O60830

Pharos - Targets

O60830

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04792 HSPB1	3	HSPB1 [cytosol] (R-HSA-450563) p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.556	3
UniProt:Q14957 GRIN2C	3	GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761) GRIN2C [plasma membrane] (R-HSA-419560) p-Y-GRIN2C [plasma membrane] (R-HSA-9612189)	0.556	3
UniProt:P06396 GSN	7	GSN(200-270) [extracellular region] (R-HSA-976940) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:P00488 F13A1	4	factor XIIIa A chain [extracellular region] (R-HSA-140788) factor XIII A chain [extracellular region] (R-HSA-140600) factor XIII A chain activation peptide [extracellular region] (R-HSA-140790) F13A1(1-731) [platelet alpha granule lumen] (R-HSA-349759)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:Q13153 PAK1	6	p-S144-PAK1 [cytosol] (R-HSA-451339) PAK1 [plasma membrane] (R-HSA-3928409) p-S144,T423-PAK1 [plasma membrane] (R-HSA-3928472) Active PAK1 [cytosol] (R-HSA-8964622) PAK1 [cytosol] (R-HSA-162629) p-S144,T423-PAK1 [cytosol] (R-HSA-399819)	0.556	3

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