Reactome | TIMM22 [mitochondrial inner membrane]

TIMM22 [mitochondrial inner membrane]

Stable Identifier

R-HSA-1252098

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Mitochondrial import inner membrane translocase subunit Tim22, TIM22_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y584 TIMM22

Gene Names

TIMM22, TEX4, TIM22

Chain

chain:1-194

Reference Genes

BioGPS Gene:29928 TIMM22

COSMIC (genes):TIMM22 TIMM22

CTD Gene:29928 TIMM22

dbSNP Gene:29928 TIMM22

ENSEMBL:ENSG00000177370 TIMM22

ENSEMBL:ENSG00000277649 TIMM22

ENSEMBL:ENSG00000278501 TIMM22

HGNC:17317 TIMM22

KEGG Gene (Homo sapiens):29928 TIMM22

Monarch:29928 TIMM22

NCBI Gene:29928 TIMM22

OMIM:607251 TIMM22

UCSC:Q9Y584 TIMM22

Reference Transcript

RefSeq:NM_013337.3 TIMM22

Other Identifiers

0005860025

11743624_a_at

16829508

219184_x_at

222841_s_at

229100_s_at

29928

3705645

3705646

3705647

3705648

3705649

3705650

3705652

3705653

3705655

3705657

49386_at

50224_s_at

8003627

A_23_P55468

GE58523

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005739

GO:0005743

GO:0006605

GO:0006626

GO:0006810

GO:0007005

GO:0008150

GO:0008320

GO:0015031

GO:0016020

GO:0016021

GO:0022857

GO:0030943

GO:0032991

GO:0042721

GO:0043226

GO:0045039

GO:0055085

GO:0061024

GO:0071806

GO:0140318

HMNXSV003044963

Hs.87595.0.S1_3p_a_at

Hs.87595.1.A1_3p_a_at

ILMN_1706959

PH_hs_0004919

TC17000007.hg

g7019552_3p_a_at

Participates

as a component of

TIMM9:TIMM10:TIMM10B:TIM22:Protein [mitochondrial inner membrane] (Homo sapiens)

as a candidate of

as an input of

TIMM9:TIMM10 transfers proteins to TIMM22 (Homo sapiens)

Other forms of this molecule

TIMM22 [mitochondrial intermembrane space]

TIMM22 [cytosol]

Inferred To

tim22 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

TIMM22 [mitochondrial inner membrane] (Caenorhabditis elegans)

TIMM22 [mitochondrial inner membrane] (Canis familiaris)

TIMM22 [mitochondrial inner membrane] (Plasmodium falciparum)

TIM22 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

timm22 [mitochondrial inner membrane] (Danio rerio)

Tim22 [mitochondrial inner membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_037469.2

OpenTargets

ENSG00000177370

GeneCards

Q9Y584

HPA

ENSG00000177370-TIMM22

Ensembl

ENSG00000278501, ENSG00000277649, ENSP00000478463, ENST00000617832, ENST00000613269, ENSP00000482204, ENST00000327158, ENSG00000177370, ENSP00000320236

PRO

Q9Y584

Pharos - Targets

Q9Y584

PDB

7CGP

Interactors (3)

Accession	Confidence Score	Evidence (IntAct)
UniProt:Q9H6H4 REEP4	0.556	3
UniProt:Q9NUH8 TM14B	0.556	3
UniProt:A8MQ03 CRTP1	0.556	3