Reactome | SHC1 binds P-ERBB4 isoform dimers

SHC1 binds P-ERBB4 isoform dimers

Stable Identifier

R-HSA-1250357

Type

Reaction [binding]

Species

Homo sapiens

Compartment

plasma membrane, cytosol, extracellular region

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Phosphorylated tyrosine residues in the C-tail of phosphorylated ERBB4 isoform dimers P-ERBB4jmAcyt1, P-ERBB4jmAcyt2 and P-ERBB4jmBcyt1 recruit SHC1 (Cohen et al. 1996, Pinkas-Kramarski et al. 1996, Kaushansky et al. 2008).

Literature References

PubMed ID	Title	Journal	Year
18721752	System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties Kaushansky, A, Gordus, A, Budnik, BA, Lane, WS, Rush, J, MacBeath, G	Chem Biol	2008
8665853	Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions Pinkas-Kramarski, R, Soussan, L, Waterman, H, Levkowitz, G, Alroy, I, Klapper, L, Lavi, S, Seger, R, Ratzkin, BJ, Sela, M, Yarden, Y	EMBO J	1996
8617750	HER4-mediated biological and biochemical properties in NIH 3T3 cells. Evidence for HER1-HER4 heterodimers Cohen, BD, Green, JM, Foy, L, Fell, HP	J Biol Chem	1996