Phosphorylation of SHC1 by ERBB4 homodimers

Stable Identifier
R-HSA-1250348
Type
Reaction
Species
Homo sapiens
Compartment
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After binding ERBB4 homodimers, SHC1 gets phosphorylated on tyrosine residues Y349 and Y350 (Kainulainen et al. 2000).

Literature References
PubMed ID Title Journal Year
10722704 A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxis

Santiestevan, E, Sundvall, M, Kainulainen, V, Määttä, JA, Elenius, K, Klagsbrun, M

J Biol Chem 2000
Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of SHC1:p-ERBB4 [plasma membrane]

Orthologous Events
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