After binding ERBB4 homodimers, SHC1 gets phosphorylated on tyrosine residues Y349 and Y350 (Kainulainen et al. 2000).
Santiestevan, E, Sundvall, M, Kainulainen, V, Määttä, JA, Elenius, K, Klagsbrun, M
protein tyrosine kinase activity of SHC1:p-ERBB4 [plasma membrane]
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