Reactome | RHAG transports CO2 from cytosol to extracellular region

RHAG transports CO2 from cytosol to extracellular region

Stable Identifier

R-HSA-1247645

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol, extracellular region, plasma membrane

Synonyms

RhAG passively translocates carbon dioxide from the cytosol to the extracellular region

ReviewStatus

5/5

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RHAG transports CO2 from cytosol to extracellular region

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The Rhesus blood group type A glycoprotein (RhAG) passively transports carbon dioxide (CO2) across the plasma membrane according to the concentration gradient (Endeward et al. 2006, Endeward et al. 2008, Musa-Aziz et al. 2009).

Literature References

PubMed ID	Title	Journal	Year
19273840	Relative CO2/NH3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG Pelletier, MF, Chen, LM, Boron, WF, Musa-Aziz, R	Proc Natl Acad Sci U S A	2009
16563834	Red cell membrane CO2 permeability in normal human blood and in blood deficient in various blood groups, and effect of DIDS Cartron, JP, Endeward, V, Gros, G, Ripoche, P	Transfus Clin Biol	2006
17712059	RhAG protein of the Rhesus complex is a CO2 channel in the human red cell membrane Cartron, JP, Endeward, V, Gros, G, Ripoche, P	FASEB J	2008