RhAG passively translocates carbon dioxide from the cytosol to the extracellular region

Stable Identifier
R-HSA-1247645
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The Rhesus blood group type A glycoprotein (RhAG) passively transports carbon dioxide (CO2) across the plasma membrane according to the concentration gradient (Endeward et al. 2006, Endeward et al. 2008, Musa-Aziz et al. 2009).

Literature References
PubMed ID Title Journal Year
16563834 Red cell membrane CO2 permeability in normal human blood and in blood deficient in various blood groups, and effect of DIDS

Endeward, V, Cartron, JP, Ripoche, P, Gros, G

Transfus Clin Biol 2006
19273840 Relative CO2/NH3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG

Musa-Aziz, R, Chen, LM, Pelletier, MF, Boron, WF

Proc Natl Acad Sci U S A 2009
17712059 RhAG protein of the Rhesus complex is a CO2 channel in the human red cell membrane

Endeward, V, Cartron, JP, Ripoche, P, Gros, G

FASEB J 2008
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Event Information
Catalyst Activity
Catalyst Activity
Title
carbon dioxide transmembrane transporter activity of RHAG [plasma membrane]
Physical Entity
Activity
Orthologous Events
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