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ZNF425 [nucleoplasm]
Stable Identifier
R-HSA-1247527
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Zinc finger protein 425, ZN425_HUMAN
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Regulation of endogenous retroelements (Homo sapiens)
Regulation of endogenous retroelements by KRAB-ZFP proteins (Homo sapiens)
ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Homo sapiens)
ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Homo sapiens)
CBX5:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement [nucleoplasm] (Homo sapiens)
SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
KRAB-ZFP binds retroelement DNA in chromatin (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
NuRD complex binds SUMO2-6K-TRIM28:KRAB-ZNF:retroelement (Homo sapiens)
NuRD:SUMO2-6K-TRIM28:KRAB-ZNF:retroelement chromatin [nucleoplasm] (Homo sapiens)
SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Homo sapiens)
ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin with H3K9me3 [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin with H3K9me3 [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
TRIM28 (KAP1) binds KRAB-ZFP in KRAB-ZFP:retroelement chromatin (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
TRIM28 in TRIM28:KRAB-ZFP:retroelement chromatin autoSUMOylates with SUMO2 (Homo sapiens)
SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Homo sapiens)
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
KRAB-ZNF / KAP Interaction (Homo sapiens)
KRAB-ZNF / KAP Complex [nucleoplasm] (Homo sapiens)
KRAB-ZNF [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
KRAB-ZNF [nucleoplasm] (Homo sapiens)
ZNF425 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6IV72 ZNF425
Gene Names
ZNF425
Chain
chain:1-752
Reference Genes
BioGPS Gene:155054 ZNF425
COSMIC (genes):ZNF425 ZNF425
CTD Gene:155054 ZNF425
dbSNP Gene:155054 ZNF425
ENSEMBL:ENSG00000204947 ZNF425
HGNC:20690 ZNF425
KEGG:hsa:155054 ZNF425
Monarch:155054 ZNF425
NCBI Gene:155054 ZNF425
OMIM:619507 ZNF425
UCSC:Q6IV72 ZNF425
Reference Transcript
RefSeq:NM_001001661.2 ZNF425
Other Identifiers
11731826_at
11731827_at
155054
17064160
242684_PM_at
242684_at
3078494
3078495
3078496
3078497
3078498
3078499
3078500
3078501
3078502
3078503
3078504
3078505
3078506
3078507
3078508
3078509
67396_at
76454_at
8143702
A_24_P941166
GE580466
GO:0000122
GO:0000977
GO:0000981
GO:0001227
GO:0003677
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0006355
GO:0006357
GO:0043226
GO:0045892
GO:0046872
GO:0140110
HMNXSV003015223
Hs.184599.0.A1_3p_at
ILMN_1683932
PH_hs_0031141
TC07001997.hg
Participates
as a candidate of
KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Homo sapiens)
KRAB-ZNF [nucleoplasm] (Homo sapiens)
Inferred To
sens-2 [nucleoplasm]
(Drosophila melanogaster)
Homologues of ZNF425 [nucleoplasm]
(Drosophila melanogaster)
ZNF425 [nucleoplasm]
(Drosophila melanogaster)
ZNF425 [nucleoplasm]
(Gallus gallus)
Cross References
ENSEMBL
ENST00000378061
,
ENSP00000367300
OpenTargets
ENSG00000204947
HPA
ENSG00000204947-ZNF425
PRO
Q6IV72
Pharos - Targets
Q6IV72
GlyGen
Q6IV72
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