ERBB3 binds neuregulins

Stable Identifier
R-HSA-1247497
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, extracellular region
ReviewStatus
5/5
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ERBB3 binds neuregulins
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ERBB3 becomes activated by binding either neuregulin 1 (NRG1) or neuregulin 2 (NRG2).
Literature References
PubMed ID Title Journal Year
7929212 ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms

Tzahar, E, Levkowitz, G, Karunagaran, D, Yi, L, Peles, E, Lavi, S, Chang, D, Liu, N, Yayon, A, Wen, D

J Biol Chem 1994
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Orthologous Events
ERBB3 binds neuregulins (Bos taurus)
ERBB3 binds neuregulins (Canis familiaris)
ERBB3 binds neuregulins (Danio rerio)
ERBB3 binds neuregulins (Drosophila melanogaster)
ERBB3 binds neuregulins (Gallus gallus)
ERBB3 binds neuregulins (Mus musculus)
ERBB3 binds neuregulins (Rattus norvegicus)
ERBB3 binds neuregulins (Sus scrofa)
Authored
Orlic-Milacic, M  (2011-11-04)
Reviewed
Neckers, LM  (2011-11-11)
Xu, W  (2011-11-11)
Created
Orlic-Milacic, M  (2011-04-01)
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