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Dehydration of methylthio-ribulose-P
Stable Identifier
R-HSA-1237140
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Sulfur amino acid metabolism (Homo sapiens)
Methionine salvage pathway (Homo sapiens)
Dehydration of methylthio-ribulose-P (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The human enzyme with 5'-methylthio ribulose-1-phosphate isomerase activity is probably produced from the APIP gene, according to its orthology with the yeast Mde1p enzyme.
Participants
Input
MTRIBUP [cytosol]
Output
2,3-DMPP [cytosol]
H2O [cytosol]
Participates
as an event of
Methionine salvage pathway (Homo sapiens)
Event Information
Go Biological Process
L-methionine salvage from methylthioadenosine (0019509)
Catalyst Activity
methylthioribulose 1-phosphate dehydratase activity of APIP:Zn++ [cytosol]
Physical Entity
APIP:Zn++ [cytosol]
(Homo sapiens)
Activity
methylthioribulose 1-phosphate dehydratase activity (GO:0046570)
Inferred From
Dehydration of methylthio-ribulose-P (Saccharomyces cerevisiae)
Cross References
Rhea
15550
Authored
Stephan, R (2010-10-24)
Reviewed
D'Eustachio, P (2011-05-23)
Created
Jassal, B (2011-03-30)
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