Upon phagolysosomal proteolysis the phagocytosed proteins still need to gain access to the cytosol for proteasomal access, transport into the ER and loading onto MHC class I. The mechanism for this escape of phagocytosed antigens remain unknown.
Kovacsovics-Bankowski, M, Rock, KL
Huang, AY, Bruce, AT, Pardoll, DM, Levitsky, HI
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