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Internalization of receptor bound antigen into clathrin coted vesicles
Stable Identifier
R-HSA-1236941
Type
Reaction [transition]
Species
Homo sapiens
Compartment
clathrin-coated endocytic vesicle membrane
,
plasma membrane
,
extracellular region
ReviewStatus
5/5
Locations in the PathwayBrowser
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Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing-Cross presentation (Homo sapiens)
Cross-presentation of soluble exogenous antigens (endosomes) (Homo sapiens)
Internalization of receptor bound antigen into clathrin coted vesicles (Homo sapiens)
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Receptor-bound exogenous antigens in coated pits on the cell surface are internalized into clathrin-coated vesicles.
Literature References
PubMed ID
Title
Journal
Year
18249105
Endocytosis mechanisms and the cell biology of antigen presentation
Kurts, C
,
Burgdorf, S
Curr Opin Immunol
2008
12061891
Phagosome maturation: aging gracefully
Botelho, RJ
,
Vieira, OV
,
Grinstein, S
Biochem J
2002
19317650
Mechanisms of endocytosis
McMahon, HT
,
Doherty, GJ
Annu Rev Biochem
2009
Participants
Input
MR:soluble antigen [plasma membrane]
(Homo sapiens)
Output
MR:soluble antigen [clathrin-coated endocytic vesicle membrane]
(Homo sapiens)
Participates
as an event of
Cross-presentation of soluble exogenous antigens (endosomes) (Homo sapiens)
Orthologous Events
Internalization of receptor bound antigen into clathrin coted vesicles (Bos taurus)
Internalization of receptor bound antigen into clathrin coted vesicles (Caenorhabditis elegans)
Internalization of receptor bound antigen into clathrin coted vesicles (Canis familiaris)
Internalization of receptor bound antigen into clathrin coted vesicles (Danio rerio)
Internalization of receptor bound antigen into clathrin coted vesicles (Drosophila melanogaster)
Internalization of receptor bound antigen into clathrin coted vesicles (Gallus gallus)
Internalization of receptor bound antigen into clathrin coted vesicles (Mus musculus)
Internalization of receptor bound antigen into clathrin coted vesicles (Rattus norvegicus)
Internalization of receptor bound antigen into clathrin coted vesicles (Sus scrofa)
Internalization of receptor bound antigen into clathrin coted vesicles (Xenopus tropicalis)
Authored
Garapati, P V (2011-03-28)
Reviewed
English, L (2011-05-13)
Desjardins, M (2011-05-13)
Created
Garapati, P V (2011-03-28)
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