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FCGR1A [early endosome membrane]
Stable Identifier
R-HSA-1236890
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
early endosome membrane
Synonyms
High affinity immunoglobulin gamma Fc receptor I precursor, FCG1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing-Cross presentation (Homo sapiens)
Cross-presentation of soluble exogenous antigens (endosomes) (Homo sapiens)
Exogenous soluble antigen targeted to more stable early endosome (Homo sapiens)
MR/other probable receptors [early endosome membrane] (Homo sapiens)
FCGR [early endosome membrane] (Homo sapiens)
FCGR1A [early endosome membrane] (Homo sapiens)
MR:soluble antigen [early endosome membrane] (Homo sapiens)
MR/other probable receptors [early endosome membrane] (Homo sapiens)
FCGR [early endosome membrane] (Homo sapiens)
FCGR1A [early endosome membrane] (Homo sapiens)
Movement of clathrin coated vesicles into early endosome (Homo sapiens)
MR:soluble antigen [early endosome membrane] (Homo sapiens)
MR/other probable receptors [early endosome membrane] (Homo sapiens)
FCGR [early endosome membrane] (Homo sapiens)
FCGR1A [early endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P12314 FCGR1A
Gene Names
FCGR1A, FCG1, FCGR1, IGFR1
Chain
signal peptide:1-15, chain:16-374
Reference Genes
BioGPS Gene:2209 FCGR1A
COSMIC (genes):FCGR1A FCGR1A
CTD Gene:2209 FCGR1A
dbSNP Gene:2209 FCGR1A
ENSEMBL:ENSG00000150337 FCGR1A
HGNC:3613 FCGR1A
KEGG:hsa:2209 FCGR1A
Monarch:2209 FCGR1A
NCBI Gene:2209 FCGR1A
OMIM:146760 FCGR1A
UCSC:P12314 FCGR1A
Reference Transcript
RefSeq:NM_000566.3 FCGR1A
Other Identifiers
11736311_x_at
11736312_s_at
11762676_x_at
16670367
214511_PM_x_at
214511_x_at
216950_PM_s_at
216950_s_at
2209
2357856
2357857
2357858
2357859
2357862
2357863
2357864
2357867
2357868
2357869
2357870
2357871
2357872
37220_at
53936_at
7905047
7905060
7919133
A_14_P110375
A_14_P119044
A_21_P0010560
A_21_P0010561
A_21_P0010727
A_23_P63390
GE60514
GO:0001788
GO:0001798
GO:0001805
GO:0002376
GO:0005515
GO:0005886
GO:0006898
GO:0006910
GO:0006911
GO:0006954
GO:0006955
GO:0007165
GO:0007166
GO:0009617
GO:0009897
GO:0016020
GO:0016192
GO:0019770
GO:0019771
GO:0019864
GO:0019884
GO:0030669
GO:0031901
GO:0038094
GO:0042590
GO:0042742
GO:0045087
GO:0050766
GO:0050776
GO:0060089
GO:0061024
GO:0098542
HMNXSV003021824
HMNXSV003023353
HMNXSV003024073
HMNXSV003057209
Hs.77424.1.S1_3p_s_at
Hs.77424.2.S1_3p_a_at
ILMN_1654389
ILMN_2176063
ILMN_2261600
ILMN_2391051
M63835_at
PH_hs_0004461
PH_hs_0035290
TC01001161.hg
TC01001172.hg
TC01003057.hg
TC01004727.hg
Participates
as a member of
FCGR [early endosome membrane] (Homo sapiens)
Other forms of this molecule
FCGR1A [clathrin-coated endocytic vesicle membrane]
FCGR1A [plasma membrane]
Inferred To
Fcgr1a [early endosome membrane]
(Rattus norvegicus)
LOC100494132 [early endosome membrane]
(Xenopus tropicalis)
Fcgr1 [early endosome membrane]
(Mus musculus)
Homologues of FCGR1A [early endosome membrane]
(Xenopus tropicalis)
FCGR1A [early endosome membrane]
(Bos taurus)
FCGR1A [early endosome membrane]
(Canis familiaris)
FCGR1A [early endosome membrane]
(Gallus gallus)
FCGR1A [early endosome membrane]
(Sus scrofa)
LOC105948225 [early endosome membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_000557.1
ENSEMBL
ENSP00000358165
,
ENST00000369168
OpenTargets
ENSG00000150337
HPA
ENSG00000150337-FCGR1A
ZINC - Substances
FCGR1_HUMAN
ZINC target
P12314
PRO
P12314
Pharos - Targets
P12314
GlyGen
P12314
ZINC - Predictions - Purchasable
FCGR1_HUMAN
PDB
3RJD
,
8DIN
,
8DJ7
,
4W4O
,
8DIR
,
4ZNE
,
4X4M
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15848 ADIPOQ
1
ADIPOQ [extracellular region]
(R-HSA-1183052)
0.556
3
UniProt:Q86VB7 CD163
5
CD163(1051-1156) [plasma membrane]
(R-HSA-9662797)
sCD163 [extracellular region]
(R-HSA-9662833)
sCD163 [cytosol]
(R-HSA-9663456)
CD163 [endocytic vesicle membrane]
(R-HSA-2230974)
CD163 [plasma membrane]
(R-HSA-2168868)
0.556
3
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