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TAP2 [phagocytic vesicle membrane]
Stable Identifier
R-HSA-1236821
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
phagocytic vesicle membrane
Synonyms
Antigen peptide transporter 2, TAP2_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing-Cross presentation (Homo sapiens)
ER-Phagosome pathway (Homo sapiens)
CALR, TAP, TAPBP dissociate from SEC22B:STX4 (Homo sapiens)
TAP [phagocytic vesicle membrane] (Homo sapiens)
TAP2 [phagocytic vesicle membrane] (Homo sapiens)
Translocation of antigenic peptides back to phagosomes via TAP (Homo sapiens)
TAP [phagocytic vesicle membrane] (Homo sapiens)
TAP2 [phagocytic vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q03519 TAP2
Gene Names
TAP2, ABCB3, PSF2, RING11, Y1
Chain
chain:1-686
Reference Genes
BioGPS Gene:6891 TAP2
COSMIC (genes):TAP2 TAP2
CTD Gene:6891 TAP2
dbSNP Gene:6891 TAP2
ENSEMBL:ENSG00000204267 TAP2
HGNC:44 TAP2
KEGG:hsa:6891 TAP2
Monarch:6891 TAP2
NCBI Gene:6891 TAP2
OMIM:170261 TAP2
UCSC:Q03519 TAP2
Reference Transcript
RefSeq:NM_001290043.1 TAP2
RefSeq:NM_018833.2 TAP2
RefSeq:NM_000544.3 TAP2
Other Identifiers
11723058_a_at
11723059_a_at
11741632_a_at
11745266_x_at
17017947
17027101
17029745
17032433
17034759
17037228
17039945
204769_PM_s_at
204769_s_at
204770_PM_at
204770_at
208428_PM_at
208428_at
225973_PM_at
225973_at
2950168
2950169
2950170
2950171
2950172
2950173
2950174
2950175
2950176
2950177
2950178
2950179
2950181
2950182
2950183
2950184
2950185
2950187
2950188
2950189
2950190
2950191
2950192
2950193
2950195
2950196
2950198
2950222
39988_at
55051_at
6891
8125483
8178841
8180034
A_23_P214444
A_23_P368067
A_33_P3214650
GE592299
GE82445
GO:0001913
GO:0001916
GO:0002237
GO:0002250
GO:0002376
GO:0002481
GO:0002485
GO:0002489
GO:0003824
GO:0005215
GO:0005515
GO:0005524
GO:0005783
GO:0005789
GO:0015031
GO:0015433
GO:0015440
GO:0015833
GO:0016020
GO:0016607
GO:0016787
GO:0016887
GO:0019885
GO:0023029
GO:0030670
GO:0033116
GO:0042287
GO:0042605
GO:0042824
GO:0042825
GO:0043226
GO:0046872
GO:0046967
GO:0046968
GO:0046978
GO:0046980
GO:0055085
GO:0140359
GO:0140657
GO:1904680
HMNXSV003011657
HMNXSV003035932
Hs.8208.0.A1_3p_at
ILMN_1759250
ILMN_1777565
M74447_at
PH_hs_0000060
TC06003604.hg
TC06004126.hg
TC6_apd_hap1000130.hg
TC6_cox_hap2000257.hg
TC6_dbb_hap3000242.hg
TC6_mann_hap4000165.hg
TC6_mcf_hap5000225.hg
TC6_qbl_hap6000185.hg
TC6_ssto_hap7000213.hg
g188505_3p_a_at
g9961245_3p_at
g9961247_3p_at
Participates
as a component of
TAP [phagocytic vesicle membrane] (Homo sapiens)
Other forms of this molecule
TAP2 [endoplasmic reticulum membrane]
TAP2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
Inferred To
Homologues of TAP2 [phagocytic vesicle membrane]
(Caenorhabditis elegans)
haf-9 [phagocytic vesicle membrane]
(Caenorhabditis elegans)
TAP2 [phagocytic vesicle membrane]
(Bos taurus)
TAP2 [phagocytic vesicle membrane]
(Mus musculus)
TAP2 [phagocytic vesicle membrane]
(Rattus norvegicus)
TAP2 [phagocytic vesicle membrane]
(Sus scrofa)
haf-4 [phagocytic vesicle membrane]
(Caenorhabditis elegans)
haf-8 [phagocytic vesicle membrane]
(Caenorhabditis elegans)
haf-7 [phagocytic vesicle membrane]
(Caenorhabditis elegans)
haf-2 [phagocytic vesicle membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001276972.1
,
NP_000535.3
,
NP_061313.2
Guide to Pharmacology - Targets
770
OpenTargets
ENSG00000204267
ENSEMBL
ENSP00000387553
,
ENSP00000513733
,
ENSP00000394101
,
ENST00000698440
,
ENSP00000372599
,
ENST00000698448
,
ENST00000374897
,
ENST00000426977
,
ENST00000383240
,
ENST00000443713
,
ENST00000439425
,
ENSP00000401377
,
ENST00000414145
,
ENST00000383239
,
ENSP00000390013
,
ENSP00000392172
,
ENSP00000372727
,
ENSP00000372600
,
ENST00000383119
,
ENST00000383118
,
ENSP00000396156
,
ENST00000451907
,
ENSP00000513722
,
ENST00000652259
,
ENSP00000498827
,
ENST00000419142
,
ENSP00000364032
,
ENSP00000372726
HPA
ENSG00000204267-TAP2
PRO
Q03519
Pharos - Targets
Q03519
GlyGen
Q03519
Orphanet
TAP2
HMDB Protein
HMDBP10765
PDB
8T4J
,
8T4H
,
8T4I
,
5U1D
,
8T4F
,
8T46
,
8T4G
,
8T4E
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O15533 TAPBP
3
TAPBP [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983083)
TAPBP [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-8863976)
TAPBP [phagocytic vesicle membrane]
(R-HSA-1236750)
0.677
8
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