Reactome | SEC61A1 [phagocytic vesicle membrane]

SEC61A1 [phagocytic vesicle membrane]

Stable Identifier

R-HSA-1236813

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

phagocytic vesicle membrane

Synonyms

Protein transport protein Sec61 subunit alpha isoform 1, S61A1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P61619 SEC61A1

Gene Names

SEC61A1, SEC61A

Chain

chain:1-476

Reference Genes

BioGPS Gene:29927 SEC61A1

COSMIC (genes):SEC61A1 SEC61A1

CTD Gene:29927 SEC61A1

dbSNP Gene:29927 SEC61A1

ENSEMBL:ENSG00000058262 SEC61A1

HGNC:18276 SEC61A1

KEGG Gene (Homo sapiens):29927 SEC61A1

Monarch:29927 SEC61A1

NCBI Gene:29927 SEC61A1

OMIM:609213 SEC61A1

UCSC:P61619 SEC61A1

Reference Transcript

RefSeq:NM_013336.3 SEC61A1

Other Identifiers

0000540497

11739107_a_at

11749955_a_at

11755426_x_at

16945189

217716_s_at

22076

222385_x_at

2641041

2641042

2641043

2641044

2641045

2641046

2641047

2641048

2641049

2641050

2641052

2641053

2641057

2641058

2641061

2641063

2641064

2641065

2641066

2641067

2641068

2641069

2641070

2641071

2641072

29927

45766_at

8082408

A_14_P100422

A_23_P212458

AAD27765

AAD39847

AAK29083

AF077032

AF084458

AF346602

AK027423

AK074706

AK074907

AK074928

AK075148

AL831940

AL832821

B3KNF6

B4DR61

BAC11283

BAC11298

BAC11434

BAG51318

BAG51989

C9JXC6

CAB022076

CAD38592

CAI46127

CCDS3046

CH471052

EAW79326

EAW79327

ENSG00000058262

ENSP00000243253

ENSP00000411445

ENST00000243253

ENST00000243253.7

ENST00000424880

ENST00000424880.2

EntrezGene:29927

EntrezGene:SEC61A1

g13517988_3p_s_at

g7019414_3p_s_at

GE81823

GO:0002376

GO:0003674

GO:0005048

GO:0005262

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005783

GO:0005784

GO:0005789

GO:0005791

GO:0005829

GO:0006605

GO:0006613

GO:0006614

GO:0006616

GO:0006620

GO:0006810

GO:0006950

GO:0007029

GO:0008150

GO:0008320

GO:0015031

GO:0016020

GO:0016021

GO:0022857

GO:0030176

GO:0031204

GO:0032991

GO:0034341

GO:0039019

GO:0043022

GO:0043226

GO:0045047

GO:0048856

GO:0055085

GO:0070588

HGNC:18276

ILMN_1659564

ILMN_1696952

IPR002208

IPR019561

IPR023201

IPR030659

MIM:609213

MIM:617056

NM_013336

NP_037468

PF00344

PF10559

PH_hs_0015718

SEC61A1

SEC61A1-201

SEC61A1-202

TC03000670.hg

UPI00000041A9

UPI000050D3B7

Participant Of

hasMember

SEC61 alpha [phagocytic vesicle membrane]

Other forms of this molecule

SEC61A1 [endoplasmic reticulum membrane]

Cross References

RefSeq

NP_037468.1

OpenTargets

ENSG00000058262

HPA

ENSG00000058262-SEC61A1

GeneCards

P61619

Ensembl

ENST00000243253, ENST00000424880, ENSG00000058262, ENSP00000411445, ENSP00000243253

PRO

P61619

Orphanet

26176

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P27824 CANX	2	CANX [integral component of lumenal side of endoplasmic reticulum membrane] (R-HSA-983091) CANX [endoplasmic reticulum lumen] (R-HSA-195906)	0.597	4
UniProt:P11021 HSPA5	6	HSPA5 [cytosol] (R-HSA-5252115) HSPA5 [extracellular region] (R-HSA-351322) HSPA5 [nucleoplasm] (R-HSA-5252042) HSPA5 [endoplasmic reticulum lumen] (R-HSA-387190) HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [integral component of lumenal side of endoplasmic reticulum membrane] (R-HSA-985498)	0.558	3
UniProt:Q13418 ILK	1	ILK [cytosol] (R-HSA-432864)	0.527	2
UniProt:P04578 env	7	Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Surface protein gp120 (P04578) [cytosol] (R-HIV-189269) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211)	0.462	2