Reactome | CD207 [clathrin-coated endocytic vesicle membrane]

CD207 [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-HSA-1236762

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

C-type lectin domain family 4 member K, CLC4K_HUMAN, Langerin

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9UJ71 CD207

Gene Names

CD207, CLEC4K

Chain

chain:1-328

Reference Genes

BioGPS Gene:50489 CD207

COSMIC (genes):CD207 CD207

CTD Gene:50489 CD207

dbSNP Gene:50489 CD207

ENSEMBL:ENSG00000116031 CD207

HGNC:17935 CD207

KEGG:hsa:50489 CD207

Monarch:50489 CD207

NCBI Gene:50489 CD207

OMIM:604862 CD207

UCSC:Q9UJ71 CD207

Reference Transcript

Other Identifiers

11731903_at

16898858

220428_PM_at

220428_at

2558877

2558878

2558879

2558880

2558881

2558882

2558883

2558884

2558885

2558886

2558887

2558889

2558890

50489

8052916

A_23_P39790

GE84673

GO:0005515

GO:0005537

GO:0005886

GO:0009897

GO:0016020

GO:0030139

GO:0030246

GO:0030669

GO:0031410

GO:0031901

GO:0043226

GO:0051607

GO:0098542

ILMN_1718754

PH_hs_0011722

TC02001968.hg

g7657290_3p_at

Participates

as a member of

MR/other probable receptors [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Other forms of this molecule

CD207 [early endosome membrane]

CD207 [plasma membrane]

Inferred To

Homologues of CD207 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

Homologues of CD207 [clathrin-coated endocytic vesicle membrane] (Danio rerio)

Homologues of CD207 [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

Homologues of CD207 [clathrin-coated endocytic vesicle membrane] (Gallus gallus)

clec-47 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

Dmel\CG14500 [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

LOC116412330 [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)

Sfp24F [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

clec-88 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

Cd207 [clathrin-coated endocytic vesicle membrane] (Mus musculus)

Cd207 [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)

clec-45 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

clec-86 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

clec-199 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

CR14499 [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

si:ch211-125e6.13 [clathrin-coated endocytic vesicle membrane] (Danio rerio)

CD207 [clathrin-coated endocytic vesicle membrane] (Bos taurus)

CD207 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

CD207 [clathrin-coated endocytic vesicle membrane] (Gallus gallus)

CD207 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)

tfc [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

clec-91 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

lectin-21Ca [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

nw [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

lectin-37Da [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

clec-202 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

clec-196 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

clec-266 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

asgr1a [clathrin-coated endocytic vesicle membrane] (Danio rerio)

lectin-21Cb [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

lectin-37Db [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

lectin-24Db [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

Dmel\CG12111 [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

Dmel\CG43055 [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

clec-204 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

lectin-22C [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

BEST:GH10831 [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

lectin-29Ca [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

clec-87 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

Dmel\CG14866 [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

Dmel\CG15818 [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

cldc1 [clathrin-coated endocytic vesicle membrane] (Danio rerio)

clec-224 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

lectin-24A [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

Lectin-galC1 [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

clec-149 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

Cross References

OpenTargets

ENSG00000116031

ENSEMBL

ENSP00000386378, ENST00000410009

HPA

ENSG00000116031-CD207

PRO

Q9UJ71

Pharos - Targets

Q9UJ71

GlyGen

Q9UJ71

PDB

3P5D, 4N32, 3C22, 4N33, 4AK8, 3P7F, 3P5H, 4N34, 3P5I, 3P7G, 3P5E, 5G6U, 4N35, 3KQG, 3P7H, 3P5F, 3P5G, 7YTQ, 4N36, 7WZ8, 4N37, 4N38

HMDB Protein

HMDBP07590

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O00767 SCD	1	SCD [endoplasmic reticulum membrane] (R-HSA-400117)	0.556	3
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	2

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