Reactome | CA9 [plasma membrane]

CA9 [plasma membrane]

Stable Identifier

R-HSA-1235065

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Carbonic anhydrase 9, CAH9_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q16790 CA9

Gene Names

CA9, G250, MN

Chain

signal peptide:1-37, chain:38-459

Reference Genes

BioGPS Gene:768 CA9

COSMIC (genes):CA9 CA9

CTD Gene:768 CA9

dbSNP Gene:768 CA9

ENSEMBL:ENSG00000107159 CA9

ENSEMBL_homo_sapiens_GENE:ENSG00000107159.14 CA9

HGNC:1383 CA9

KEGG Gene (Homo sapiens):768 CA9

Monarch:768 CA9

NCBI Gene:768 CA9

OMIM:603179 CA9

UCSC:Q16790 CA9

Reference Transcript

RefSeq:NM_001216.2 CA9

Other Identifiers

11723326_at

11723327_x_at

11752982_x_at

17084723

205199_PM_at

205199_at

3168067

3168068

3168070

3168071

3168072

3168073

3168076

3168078

3168079

3168080

3168083

3168085

3168086

40309_at

768

8155083

A_14_P121177

A_23_P157793

GE59931

GO:0001666

GO:0002009

GO:0003824

GO:0004089

GO:0005515

GO:0005634

GO:0005730

GO:0005886

GO:0006730

GO:0008270

GO:0009410

GO:0016020

GO:0016323

GO:0016829

GO:0031528

GO:0033574

GO:0042995

GO:0043226

GO:0046872

GO:0046903

GO:0048856

GO:0098772

GO:0140677

HMNXSV003013010

HMNXSV003021992

HMNXSV003030692

ILMN_1725139

PH_hs_0003972

TC09000191.hg

X66839_at

g9955947_3p_at

Participates

as a component of

CA9:Zn2+ [plasma membrane] (Homo sapiens)

as an output of

Expression of Carbonic Anhydrase IX (CA9) (Homo sapiens)

Inferred To

ca9 [plasma membrane] (Xenopus tropicalis)

Car9 [plasma membrane] (Rattus norvegicus)

CA9 [plasma membrane] (Bos taurus)

CA9 [plasma membrane] (Caenorhabditis elegans)

CA9 [plasma membrane] (Canis familiaris)

CA9 [plasma membrane] (Gallus gallus)

CA9 [plasma membrane] (Mus musculus)

CA9 [plasma membrane] (Sus scrofa)

CAH2 [plasma membrane] (Drosophila melanogaster)

CAH9 [plasma membrane] (Drosophila melanogaster)

Homologues of CA9 [plasma membrane] (Caenorhabditis elegans)

Homologues of CA9 [plasma membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_001207.2

ZINC - World Drugs

CAH9_HUMAN

Guide to Pharmacology - Targets

3055

OpenTargets

ENSG00000107159

ZINC - FDA approved

CAH9_HUMAN

ZINC - Substances

CAH9_HUMAN

ZINC target

Q16790

ZINC - Biogenic

CAH9_HUMAN

PRO

Q16790

PDB

6RQU, 6FE0, 6RQW, 5DVX, 6TL6, 6QN5, 6RQQ, 6FE2, 6G98, 6G9U, 6Y74, 3IAI, 6FE1, 5FL4, 6QN2, 5FL5, 6QUT, 6TL5, 6RQN, 2HKF, 7POM, 5FL6, 6QN6

ZINC - Investigational

CAH9_HUMAN

ZINC - Metabolites

CAH9_HUMAN

IntEnz

4.2.1.1

HPA

ENSG00000107159-CA9

GeneCards

Q16790

Ensembl

ENST00000378357, ENSP00000367608, ENSG00000107159

Pharos - Targets

Q16790

ZINC - Predictions - Purchasable

CAH9_HUMAN

HMDB Protein

HMDBP03173

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O76003 GLRX3	1	GLRX3 [cytosol] (R-HSA-5691202)	0.735	9
UniProt:P21291 CSRP1	1	CSRP1 [nucleoplasm] (R-HSA-5660398)	0.556	3