VHL:EloB,C:CUL2:RBX1

Stable Identifier
R-HSA-1234141
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
9122164 The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

Pause, A, Lee, S, Worrell, RA, Chen, DY, Burgess, WH, Linehan, WM, Klausner, RD

Proc Natl Acad Sci U S A 1997
9891082 Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein

Lee, S, Neumann, M, Stearman, R, Stauber, R, Pause, A, Pavlakis, GN, Klausner, RD

Mol Cell Biol 1999
12101228 Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein

Groulx, I, Lee, S

Mol Cell Biol 2002
15601820 VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

Kamura, T, Maenaka, K, Kotoshiba, S, Matsumoto, M, Kohda, D, Conaway, RC, Conaway, JW, Nakayama, KI

Genes Dev 2004
Participants
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