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RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
Stable Identifier
R-HSA-1226088
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
p107:E2F4:DP1/2
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G0 and Early G1 (Homo sapiens)
Recruitment of HDAC1 by p107 (RBL1) (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
Transcription of E2F targets under negative control by DREAM complex (Homo sapiens)
E2F1 gene transcription is inhibited by the DREAM complex, RBL1 and RBL2 (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:E2F1 gene [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 (Homo sapiens)
CCNA2 gene expression is inhibited by RBL1 and RBL2 (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:CCNA2 gene [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
CDK1 gene expression is stimulated by E2F1 and repressed by RBL1 and RBL2 (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:CDK1 gene [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
E2F1 gene transcription is inhibited by the DREAM complex, RBL1 and RBL2 (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:E2F1 gene [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
MYBL2 gene expression is inhibited by RBL1 and RBL2 (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:MYBL2 gene [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CCNA2 gene promoter (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:CCNA2 gene [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CDK1 gene promoter (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:CDK1 gene [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds E2F1 gene promoter (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:E2F1 gene [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds MYBL2 gene promoter (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:MYBL2 gene [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 (Homo sapiens)
RBL1:E2F4:DP1/2:Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
G1 Phase (Homo sapiens)
Cyclin D associated events in G1 (Homo sapiens)
Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
G1/S Transition (Homo sapiens)
G1/S-Specific Transcription (Homo sapiens)
CDK1 gene expression is stimulated by E2F1 and repressed by RBL1 and RBL2 (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:CDK1 gene [nucleoplasm] (Homo sapiens)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
Participants
components
E2F4 [nucleoplasm]
(Homo sapiens)
RBL1 [nucleoplasm]
(Homo sapiens)
TFDP1,TFDP2 [nucleoplasm]
(Homo sapiens)
Participates
as a component of
RBL1:E2F4:DP1/2:Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
as an input of
p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 (Homo sapiens)
Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Homo sapiens)
Recruitment of HDAC1 by p107 (RBL1) (Homo sapiens)
Inferred To
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
(Bos taurus)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
(Caenorhabditis elegans)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
(Canis familiaris)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
(Dictyostelium discoideum)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
(Drosophila melanogaster)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
(Gallus gallus)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
(Mus musculus)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
(Rattus norvegicus)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
(Sus scrofa)
RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
(Xenopus tropicalis)
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