TrxA/B1 reactivates Tpx

Stable Identifier
R-HSA-1222644
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
TrxA/B1 reactivates Tpx
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The Tpx peroxiredoxin is reactivated by either TrxA or TrxB1 (Jaeger et al. 2006).
Literature References
PubMed ID Title Journal Year
14871480 Multiple thioredoxin-mediated routes to detoxify hydroperoxides in Mycobacterium tuberculosis

Singh, M, Flohé, L, Radi, R, Budde, H, Jaeger, T, Trujillo, M, Menge, U

Arch Biochem Biophys 2004
Participants
Input
Output
Participates
as an event of
Catalyst Activity

disulfide oxidoreductase activity of TrxA/B1 [cytosol]

Physical Entity
TrxA/B1 [cytosol] (Mycobacterium tuberculosis)
Activity
disulfide oxidoreductase activity (GO:0015036)
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2011-01-10)
Reviewed
Warner, D  (2012-04-30)
Created
Jassal, B  (2011-02-28)
Cite Us!