Carboxymycobactin binds LTF:2xFe3+:2xCO3(2-)

Stable Identifier
R-HSA-1222641
Type
Reaction
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
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Since bacterial siderophores bind iron with much greater affinity, they can scavenge iron ions from loaded lactoferrin (Madigan et al. 2012).

Literature References
PubMed ID Title Journal Year
22232695 Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis

Layre, E, McConnell, MJ, Rodriguez, GM, Barry CE, 3rd, Debono, CA, Moody, DB, Cheng, TY, Young, DC, Murry, JP, Matsunaga, I, Rubin, EJ, Wei, JR, Madigan, CA

Proc Natl Acad Sci U S A 2012
Participants
Participates
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Reviewed
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