Loaded mycobactin gets imported

Stable Identifier
R-HSA-1222597
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The ABC-type transporter IrtA, probably complexed with IrtB and ViuB (Rv2895c), specifically transports iron-loaded mycobactin into the cytosol (Ryndak et al. 2009).

Literature References
PubMed ID Title Journal Year
19948799 The Mycobacterium tuberculosis high-affinity iron importer, IrtA, contains an FAD-binding domain

Ryndak, MB, Wang, S, Smith, I, Rodriguez, GM

J Bacteriol 2010
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
siderophore transmembrane transporter activity of IrtAB:Rv2895c [plasma membrane]
Physical Entity
Activity
Disease
Name Identifier Synonyms
tuberculosis 399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Reviewed
Created