The function of V-type proton pumping ATPases is basically the same as that of F-type ATPases, except that V-ATPases cannot synthesize ATP from the proton motive force, the reverse reaction of pumping. When pumping, ATP hydrolysis drives a 120 degree rotation of the rotor which leads to movement of three protons into the phagosome (Adachi et al. 2007).
Adachi, K, Oiwa, K, Nishizaka, T, Furuike, S, Noji, H, Itoh, H, Yoshida, M, Kinosita K, Jr
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