Lactoferrin scavenges iron ions

Stable Identifier
R-HSA-1222491
Type
Reaction [binding]
Species
Homo sapiens
Compartment
phagocytic vesicle lumen
ReviewStatus
5/5
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Lactoferrin scavenges iron ions
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Lactoferrin is secreted from many tissues to collect stray iron ions that can catalyze unwanted reactions, and to starve microorganisms of this important metal. One molecule of lactoferrin can load two ferric (Fe(3+)) ions together with two carbonate (CO3(2-)) anions (Haridas et al. 1995).

Literature References
PubMed ID Title Journal Year
15299793 Structure of human diferric lactoferrin refined at 2.2 A resolution

Haridas, M, Baker, EN, Anderson, BF

Acta Crystallogr D Biol Crystallogr 1995
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Authored
Stephan, R  (2011-01-10)
Reviewed
Warner, D  (2012-04-30)
Created
Jassal, B  (2011-02-28)
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