Peroxynitrite oxidizes Peptide-Methionine residues

Stable Identifier
R-HSA-1222411
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol
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Peroxynitrite oxidizes Peptide-Methionine residues
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Within the bacterial cell, peroxynitrite (ONOO-) is able to oxidize methionine residues on peptides, forming methionine sulfoxide residues with itself being reduced to nitrite (NOO-) (Pryor et al. 1994).

Literature References
PubMed ID Title Journal Year
7972029 One- and two-electron oxidations of methionine by peroxynitrite

Pryor, WA, Jin, X, Squadrito, GL

Proc Natl Acad Sci U S A 1994
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Participant Of
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Authored
Stephan, R  (2011-01-10)
Reviewed
Warner, D  (2012-04-30)
Created
Jassal, B  (2011-02-28)