MsrA and MsrB are enzymes that can both reduce the S- and R-stereoisomers of (peptidyl-) methionine sulfoxide. The exact nature of the accompanying thioredoxin is not settled, but it is predicted to be TrxA. The whole methionine-MsrA/B-thioredoxin-and-reductase system is an important part of NO detoxification in Mtb (St John et al. 2001, Lee et al. 2009).
St John, G, Brot, N, Ruan, J, Erdjument-Bromage, H, Tempst, P, Weissbach, H, Nathan, C
Lee, WL, Gold, B, Darby, C, Brot, N, Jiang, X, de Carvalho, LP, Wellner, D, St John, G, Jacobs WR, Jr, Nathan, C
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