Carboxymycobactin and mycobactin exchange their iron load

Stable Identifier
R-HSA-1222325
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
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Carboxymycobactin and mycobactin exchange their iron loads. This interplay between polar and nonpolar siderophore is unique to Mtb. However, mycobactin can gather iron from nonpolar regions of the host cell by itself too (Madigan et al. 2012).

Literature References
PubMed ID Title Journal Year
22232695 Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis

Madigan, CA, Cheng, TY, Layre, E, Young, DC, McConnell, MJ, Debono, CA, Murry, JP, Wei, JR, Barry CE, 3rd, Rodriguez, GM, Matsunaga, I, Rubin, EJ, Moody, DB

Proc Natl Acad Sci U S A 2012
Participants
Participant Of
Disease
Name Identifier Synonyms
tuberculosis 399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Reviewed
Created