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Me2K5-HIST2H3A [nucleoplasm]
Stable Identifier
R-HSA-1214225
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Histone H3.2 with dimethylated lysine-4, HIST2H3A, H32_HUMAN
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Prophase (Homo sapiens)
Condensation of Prophase Chromosomes (Homo sapiens)
CDK1 phosphorylates PHF8 (Homo sapiens)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
CDK1 phosphorylates condensin II subunit NCAPD3 (Homo sapiens)
Condensin II:Nucleosome with H4K20me1 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Condensin II complex binds H4K20me1-containing nucleosomes (Homo sapiens)
Condensin II:Nucleosome with H4K20me1 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Condensin II-mediated condensation of prophase chromosomes (Homo sapiens)
Hyperphosphorylated Condensin II:Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
PHF8 demethylates histone H4K20me1 (Homo sapiens)
PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
PLK1 binds phosphorylated condensin II complex (Homo sapiens)
Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
PLK1 hyperphosphorylates Condensin II complex (Homo sapiens)
Hyperphosphorylated Condensin II:Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
SETD8 monomethylates histone H4 (Homo sapiens)
PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Homo sapiens)
H3K4me2/3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Meiosis (Homo sapiens)
Meiotic recombination (Homo sapiens)
PRDM9 trimethylates histone H3 (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HDMs demethylate histones (Homo sapiens)
KDM1A, KDM1B demethylate Me2K5-histone H3 (Homo sapiens)
Me2K5-histone H3 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
KDM5A-D demethylate Me2K5-histone H3 (Homo sapiens)
Me2K5-histone H3 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
KDM5A-D demethylate Me3K5-histone H3 (Homo sapiens)
Me2K5-histone H3 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
PKMTs methylate histone lysines (Homo sapiens)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Homo sapiens)
Me2K5-histone H3 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Homo sapiens)
Me2K5-histone H3 [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX1 (Homo sapiens)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Homo sapiens)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Homo sapiens)
H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Homo sapiens)
H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Homo sapiens)
H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Homo sapiens)
H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
RUNX1 and GATA1 bind the promoter of the GP1BA gene (Homo sapiens)
H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
RUNX1 and GATA1 bind the promoter of the ITGA2B gene (Homo sapiens)
H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
RUNX1 and GATA1 bind the promoter of the MIR27A gene (Homo sapiens)
H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
RUNX1 and GATA1 bind the promoter of the THBS1 gene (Homo sapiens)
H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the GP1BA promoter (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the ITGA2B promoter (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the MIR27A gene promoter (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the THBS1 gene promoter (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Reproduction (Homo sapiens)
Meiosis (Homo sapiens)
Meiotic recombination (Homo sapiens)
PRDM9 trimethylates histone H3 (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Estrogen-dependent gene expression (Homo sapiens)
Binding of AP1 transcriptional activator complexes to CCND1 promoter (Homo sapiens)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3:ESTG:ESR1 dimer:JUN:ATF2:POUF21:ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] (Homo sapiens)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
Estrogen-responsive CCND1 gene expression (Homo sapiens)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3:ESTG:ESR1 dimer:JUN:ATF2:POUF21:ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] (Homo sapiens)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
FOXA1 and GATA3 bind to CCND1 promoter (Homo sapiens)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K4me2 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Me2K5-HIST2H3A [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q71DI3 H3C15
Gene Names
H3C15, HIST2H3A, H3C14, H3F2, H3FM, HIST2H3C, H3C13, HIST2H3D
Chain
chain:1-136
Reference Genes
BioGPS Gene:126961 H3C15
BioGPS Gene:333932 H3C15
BioGPS Gene:653604 H3C15
CTD Gene:126961 H3C15
CTD Gene:333932 H3C15
CTD Gene:653604 H3C15
dbSNP Gene:126961 H3C15
dbSNP Gene:333932 H3C15
dbSNP Gene:653604 H3C15
ENSEMBL:ENSG00000183598 HIST2H3D
ENSEMBL:ENSG00000203811 HIST2H3C
ENSEMBL:ENSG00000203852 HIST2H3A
ENSEMBL_homo_sapiens_GENE:ENSG00000183598.4 H3C15
ENSEMBL_homo_sapiens_GENE:ENSG00000203811.2 H3C15
ENSEMBL_homo_sapiens_GENE:ENSG00000203852.4 H3C15
HGNC:20503 H3C15
HGNC:20505 H3C15
HGNC:25311 H3C15
KEGG Gene (Homo sapiens):126961 H3C15
KEGG Gene (Homo sapiens):333932 H3C15
KEGG Gene (Homo sapiens):653604 H3C15
Monarch:126961 H3C15
Monarch:333932 H3C15
Monarch:653604 H3C15
NCBI Gene:126961 H3C15
NCBI Gene:333932 H3C15
NCBI Gene:653604 H3C15
OMIM:142780 H3C15
UCSC:Q71DI3 H3C15
Reference Transcript
RefSeq:NM_001123375.2 H3C15
RefSeq:NM_001005464.2 H3C15
RefSeq:NM_021059.2 H3C15
Other Identifiers
11742410_s_at
126961
16670387
16692614
16692616
2357939
2357940
2434047
2434082
2434083
333932
653604
7905085
7919589
7919612
7919614
ADDON002755.hg
ADDON002789.hg
A_23_P115375
A_24_P324465
A_24_P45651
A_33_P3257678
GE79559
GO:0000786
GO:0003677
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005694
GO:0006325
GO:0006334
GO:0030527
GO:0043226
GO:0043229
GO:0046982
GO:0065003
GO:0070062
HMNXSV003021896
HMNXSV003029395
ILMN_1664706
ILMN_1666179
PH_hs_0030802
PH_hs_0034534
TC01001175.hg
TC01003173.hg
TC01003188.hg
TC01003189.hg
Participates
as a candidate of
Me2K5-histone H3 [nucleoplasm] (Homo sapiens)
H3K4me2 [nucleoplasm] (Homo sapiens)
as a member of
Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)
Other forms of this molecule
2xAcK-HIST2H3A [nucleoplasm]
Me1K5-HIST2H3A [nucleoplasm]
Me2aR27-HIST2H3A [nucleoplasm]
Me2aR18-HIST2H3A [nucleoplasm]
Me2sR9-HIST2H3A [nucleoplasm]
Me2sR3-HIST2H3A [nucleoplasm]
AcK9,14-p-S10-HIST2H3A [nucleoplasm]
AcK14,18,79-p-S10-HIST2H3A [nucleoplasm]
AcK9,14,18-p-S10,T11-HIST2H3A [nucleoplasm]
AcK14,18-p-S10,T11-HIST2H3A [nucleoplasm]
AcK9,14,18,79-p-S10,T11-HIST2H3A [nucleoplasm]
AcK14,18-p-S10-HIST2H3A [nucleoplasm]
AcK14,18,79-p-T11-HIST2H3A [nucleoplasm]
AcK14,18-p-T11-HIST2H3A [nucleoplasm]
AcK14,18,79-p-S10,T11-HIST2H3A [nucleoplasm]
Me2K28-HIST2H3A [nucleoplasm]
MeK37-HIST2H3A [nucleoplasm]
MeK80-HIST2H3A [nucleoplasm]
Me3K80-HIST2H3A [nucleoplasm]
Me2K80-HIST2H3A [nucleoplasm]
Me3K37-HIST2H3A [nucleoplasm]
Me2K37-HIST2H3A [nucleoplasm]
MeK-HIST2H3A [nucleoplasm]
MeK28-HIST2H3A [nucleoplasm]
MeK10-HIST2H3A [cytosol]
HIST2H3A [cytosol]
Me2aR3-HIST2H3A [nucleoplasm]
MeK5-HIST2H3A [nucleoplasm]
Cit27-HIST2H3A [nucleoplasm]
Cit3-HIST2H3A [nucleoplasm]
Cit9-HIST2H3A [nucleoplasm]
Cit18-HIST2H3A [nucleoplasm]
MeR18-HIST2H3A [nucleoplasm]
MeR3-HIST2H3A [nucleoplasm]
MeR27-HIST2H3A [nucleoplasm]
MeR9-HIST2H3A [nucleoplasm]
Me2K5,Me2aR3-HIST2H3A [nucleoplasm]
Ack10-HIST2H3A [nucleoplasm]
HIST2H3A [extracellular region]
AcK24-HIST2H3A [nucleoplasm]
Ack15-HIST2H3A [nucleoplasm]
AcK19-HIST2H3A [nucleoplasm]
AcK5-HIST2H3A [nucleoplasm]
Me2K10-HIST2H3A [nucleoplasm]
p-T12-HIST2H3A [nucleoplasm]
p-T12,MeK-HIST2H3A [nucleoplasm]
p-T12, Me2K-10-HIST2H3A [nucleoplasm]
p-T12, Me3K-10-HIST2H3A [nucleoplasm]
Me3K10-HIST2H3A [nucleoplasm]
Me3K5-HIST2H3A [nucleoplasm]
Me3K28-HIST2H3A [nucleoplasm]
HIST2H3A [nucleoplasm]
Inferred To
Me2K5-HIST1H3A [nucleoplasm]
(Plasmodium falciparum)
H3a [nucleoplasm]
(Dictyostelium discoideum)
His3:CG33845 [nucleoplasm]
(Drosophila melanogaster)
CSE4 [nucleoplasm]
(Saccharomyces cerevisiae)
H3-VII [nucleoplasm]
(Gallus gallus)
hcp-3 [nucleoplasm]
(Caenorhabditis elegans)
Hist2h3c2 [nucleoplasm]
(Rattus norvegicus)
H3C15 [nucleoplasm]
(Sus scrofa)
cnp1 [nucleoplasm]
(Schizosaccharomyces pombe)
Me2K5-Hist1h3b [nucleoplasm]
(Mus musculus)
Me2K5-Histone H3.2 [nucleoplasm]
(Bos taurus)
Me2K5-HIST2H3A [nucleoplasm]
(Danio rerio)
Homologues of Me2K5-HIST1H3A [nucleoplasm]
(Plasmodium falciparum)
Modified Residues
Name
N6,N6-dimethyl-L-lysine at 5
Coordinate
5
PsiMod Name
N6,N6-dimethyl-L-lysine [MOD:00084]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6,N6-dimethyl-L-lysine.
Cross References
RefSeq
NP_001116847.1
,
NP_066403.2
,
NP_001005464.1
OpenTargets
ENSG00000203852
HPA
ENSG00000183598-H3C13
,
ENSG00000203852-H3C15
,
ENSG00000203811-H3C14
GeneCards
Q71DI3
Ensembl
ENST00000331491
,
ENST00000403683
,
ENST00000369158
,
ENSP00000333277
,
ENSG00000183598
,
ENSP00000385479
,
ENSP00000358154
,
ENSG00000203852
,
ENSG00000203811
PRO
Q71DI3
Pharos - Targets
Q71DI3
PDB
7TAN
,
7U51
,
7PEX
,
7U50
,
5CIU
,
2IIJ
,
7PF0
,
3QO2
,
7PEY
,
3R93
,
7PEV
,
7UVA
,
7JOA
,
3DB3
,
6FML
,
7PEW
,
7PFX
,
7PET
,
7PF4
,
7PFF
,
2X4X
,
7PEU
,
7PF5
,
8AV6
,
7PFE
,
2X4W
,
7PEZ
,
7BU9
,
6Y5D
,
7PF2
,
7PF3
,
5BO0
,
3AV1
,
2X4Y
,
5VAC
,
7XCR
,
7PFT
,
4OUC
,
6X5A
,
6T79
,
7XCT
,
7PFA
,
7PFU
,
6T7C
,
6T7D
,
5B0Y
,
4MZG
,
5B0Z
,
8ATF
,
6X59
,
4MZF
,
7PF6
,
7UV9
,
7JO9
,
7JZV
,
6T7B
,
8AAG
,
6Y5E
,
4MZH
,
7BQZ
,
6ACE
,
8JLB
,
7PFV
,
8OL1
,
7U53
,
3MO8
,
7U52
,
5B40
,
8JLD
,
8GRQ
,
7XD0
,
7PFD
,
7PFC
,
6XJD
,
7YRD
,
6T7A
,
7PFW
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62805 H4C1
17
polySUMO3-HIST1H4 [nucleoplasm]
(R-HSA-4570531)
monoSUMO1-HIST1H4 [nucleoplasm]
(R-HSA-4570518)
4xAcK-HIST1H4A [nucleoplasm]
(R-HSA-427390)
AcK5,12-HIST1H4A [nucleoplasm]
(R-HSA-212078)
AcK13-HIST1H4 [nucleoplasm]
(R-HSA-4568744)
Me2aR4-HIST1H4 [nucleoplasm]
(R-HSA-5229015)
Me2sR4-HIST1H4 [nucleoplasm]
(R-HSA-4754243)
MeR4-HIST1H4 [nucleoplasm]
(R-HSA-4754240)
Me3K21-HIST1H4 [nucleoplasm]
(R-HSA-5651656)
HIST1H4A [extracellular region]
(R-HSA-977569)
AcK17-HIST1H4 [nucleoplasm]
(R-HSA-427469)
AcK6-HIST1H4 [nucleoplasm]
(R-HSA-4568748)
AcK9-HIST1H4 [nucleoplasm]
(R-HSA-4568758)
MeK21-HIST1H4 [nucleoplasm]
(R-HSA-5423110)
AcK-HIST1H4 [nucleoplasm]
(R-HSA-3451124)
Me2K21-HIST1H4 [nucleoplasm]
(R-HSA-5651652)
HIST1H4 [nucleoplasm]
(R-HSA-181902)
0.704
4
UniProt:Q9Y294 ASF1A
1
ASF1A [nucleoplasm]
(R-HSA-417169)
0.576
4
UniProt:P49736 MCM2
1
MCM2 [nucleoplasm]
(R-HSA-68557)
0.576
5
UniProt:Q96CV9 OPTN
6
OPTN [recycling endosome membrane]
(R-HSA-8854141)
p-S177-OPTN [nucleoplasm]
(R-HSA-2562595)
p-S177-OPTN [cytosol]
(R-HSA-2562525)
OPTN [Golgi membrane]
(R-HSA-2161111)
OPTN [cytosol]
(R-HSA-9687907)
p-S177,S473,S513-OPTN [cytosol]
(R-HSA-9687840)
0.556
3
UniProt:P19404 NDUFV2
1
NDUFV2 [mitochondrial inner membrane]
(R-HSA-163939)
0.556
3
UniProt:P29474 NOS3
9
2xPalmC-MyrG-p-S1177,S1179-NOS3 [plasma membrane]
(R-HSA-9860783)
2xPalmC-MyrG-p-S633-NOS3 [plasma membrane]
(R-HSA-9861341)
2xPalmC-MyrG-NOS3 [endocytic vesicle membrane]
(R-HSA-535007)
2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane]
(R-HSA-202139)
MyrG-NOS3 [Golgi membrane]
(R-HSA-534995)
MyrG-NOS3 [cytosol]
(R-HSA-203687)
2xPalmC-MyrG-NOS3 [plasma membrane]
(R-HSA-534993)
2xPalmC-MyrG-NOS3 [Golgi membrane]
(R-HSA-203769)
NOS3 [cytosol]
(R-HSA-202114)
0.556
3
UniProt:P37840 SNCA
5
SNCA A30P [cytosol]
(R-HSA-5658569)
SNCA [extracellular region]
(R-HSA-976954)
Ub-SNCA [cytosol]
(R-HSA-5660754)
p-S129-SNCA [cytosol]
(R-HSA-9836432)
SNCA [cytosol]
(R-HSA-5658500)
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
18
UniProt:P14136 GFAP
3
p-GFAP [lysosomal membrane]
(R-HSA-9626054)
GFAP [lysosomal membrane]
(R-HSA-9625195)
GFAP [cytosol]
(R-HSA-1253311)
0.556
3
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