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Fertilization
Stable Identifier
R-HSA-1187000
DOI
10.3180/REACT_163914.1
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Reproduction (Homo sapiens)
Fertilization (Homo sapiens)
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Mammalian fertilization comprises sperm migration through the female reproductive tract, biochemical and morphological changes to sperm, and sperm-egg interaction in the oviduct. Although the broad concepts of fertilization are well defined, our understanding of the biochemical mechanisms underlying sperm-egg binding is limited.
Literature References
PubMed ID
Title
Journal
Year
16467268
Analysis of the human sperm proteome
Johnston, DS
,
Kopf, GS
,
Wooters, J
,
Roberts, KP
,
Qiu, Y
Ann N Y Acad Sci
2005
12479616
The state of the union: the cell biology of fertilization
Florman, HM
,
Evans, JP
Nat Cell Biol
2002
Participants
Events
Sperm Motility And Taxes
(Homo sapiens)
Interaction With Cumulus Cells And The Zona Pellucida
(Homo sapiens)
Acrosome Reaction and Sperm:Oocyte Membrane Binding
(Homo sapiens)
Participates
as an event of
Reproduction (Homo sapiens)
Event Information
Go Biological Process
single fertilization (0007338)
Orthologous Events
Fertilization (Bos taurus)
Fertilization (Caenorhabditis elegans)
Fertilization (Canis familiaris)
Fertilization (Danio rerio)
Fertilization (Dictyostelium discoideum)
Fertilization (Drosophila melanogaster)
Fertilization (Gallus gallus)
Fertilization (Mus musculus)
Fertilization (Plasmodium falciparum)
Fertilization (Rattus norvegicus)
Fertilization (Sus scrofa)
Fertilization (Xenopus tropicalis)
Authored
Gillespie, ME (2013-02-13)
Reviewed
Lishko, PV (2013-05-21)
Created
Gillespie, ME (2011-02-10)
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