The Adiponectin gene is transcribed to yield mRNA and the mRNA is translated to yield protein. Expression of Adiponectin is upregulated during adipogenesis by C/EBPalpha (CEBPA), PPARG, and CEBPB (Segawa et al. 2009, Qiao et al. 2005, Iwaki et al. 2003, Kita et al. 2005).
Kita, A, Yamasaki, H, Kuwahara, H, Moriuchi, A, Fukushima, K, Kobayashi, M, Fukushima, T, Takahashi, R, Abiru, N, Uotani, S, Kawasaki, E, Eguchi, K
Segawa, K, Matsuda, M, Fukuhara, A, Morita, K, Okuno, Y, Komuro, R, Shimomura, I
Qiao, L, Maclean, PS, Schaack, J, Orlicky, DJ, Darimont, C, Pagliassotti, M, Friedman, JE, Shao, J
Iwaki, M, Matsuda, M, Maeda, N, Funahashi, T, Matsuzawa, Y, Makishima, M, Shimomura, I
C/EBPbeta (CEBPB) binds the promoter of the Adiponectin gene and activates transcription.
The PPARG:RXRA heterodimer activated by a thiazolidinedione agonist binds the promoter of the Adiponectin gene and activates transcription.
C/EBPalpha (CEBPA) binds the promoter of the Adiponectin gene and activates transcription.
© 2021 Reactome
