LEFTY binds NODAL

Stable Identifier
R-HSA-1181352
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
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LEFTY binds NODAL
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As inferred from mouse (Chen and Shen 2004) both LEFTY1 and LEFTY2 can bind NODAL and inhibit NODAL signaling. The stoichiometry of the resulting LEFTY:NODAL complex is unknown.

Literature References
PubMed ID Title Journal Year
15062104 Two modes by which Lefty proteins inhibit nodal signaling

Chen, C, Shen, MM

Curr Biol 2004
Participants
Input
Output
Participates
as an event of
Inferred From
Lefty binds Nodal (Mus musculus)
Authored
May, B  (2011-01-28)
Reviewed
Peng, C  (2011-08-25)
Created
May, B  (2011-02-05)
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