LEFTY binds NODAL

Stable Identifier
R-HSA-1181352
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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As inferred from mouse (Chen and Shen 2004) both LEFTY1 and LEFTY2 can bind NODAL and inhibit NODAL signaling. The stoichiometry of the resulting LEFTY:NODAL complex is unknown.
Literature References
PubMed ID Title Journal Year
15062104 Two modes by which Lefty proteins inhibit nodal signaling

Chen, C, Shen, MM

Curr Biol 2004
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