LEFTY binds the EGF-CFC coreceptor in the NODAL receptor

Stable Identifier
R-HSA-1181351
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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LEFTY1 and LEFTY2 are able to inhibit NODAL signaling by binding the EGF-CFC coreceptor (CRIPTO or CRYPTIC) and thereby preventing the coreceptor from interacting with other components of the NODAL receptor.

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