Reactome | CTSF [lysosomal lumen]

CTSF [lysosomal lumen]

Stable Identifier

R-HSA-1181231

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal lumen

Synonyms

Cathepsin F, CATF_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UBX1 CTSF

Gene Names

CTSF

Chain

signal peptide:1-19, propeptide:20-270, chain:271-484

Reference Genes

BioGPS Gene:8722 CTSF

COSMIC (genes):CTSF CTSF

CTD Gene:8722 CTSF

dbSNP Gene:8722 CTSF

ENSEMBL:ENSG00000174080 CTSF

HGNC:2531 CTSF

Monarch:8722 CTSF

NCBI Gene:8722 CTSF

OMIM:603539 CTSF

UCSC:Q9UBX1 CTSF

Reference Transcript

RefSeq:NM_003793.3 CTSF

Other Identifiers

11717500_a_at

16740828

203657_PM_s_at

203657_s_at

3378343

3378345

3378346

3378347

3378348

3378349

3378350

3378351

3378352

3378353

3378354

3378355

3378356

3378357

3378358

3378359

3378360

3378361

3378362

3378363

3378364

3378365

3378366

3378367

39846_at

7949650

8722

A_23_P24433

GE62757

GO:0002376

GO:0003824

GO:0004197

GO:0005615

GO:0005764

GO:0005773

GO:0005783

GO:0005886

GO:0006508

GO:0008234

GO:0016787

GO:0019886

GO:0030312

GO:0031012

GO:0043202

GO:0043226

GO:0043231

GO:0051603

GO:0062023

GO:0070062

GO:0140096

GO:1903561

HMNXSV003013437

ILMN_1804955

PH_hs_0001105

TC11001971.hg

g6042195_3p_a_at

Participates

as a candidate of

Cathepsin [lysosomal lumen] (Homo sapiens)

as a member of

Cathepsin [lysosomal lumen] (Homo sapiens)

Inferred To

cprA [lysosomal lumen] (Dictyostelium discoideum)

CTSF [lysosomal lumen] (Bos taurus)

CTSF [lysosomal lumen] (Canis familiaris)

CTSF [lysosomal lumen] (Dictyostelium discoideum)

CTSF [lysosomal lumen] (Plasmodium falciparum)

CTSF [lysosomal lumen] (Sus scrofa)

Homologues of CTSF [lysosomal lumen] (Dictyostelium discoideum)

Homologues of CTSF [lysosomal lumen] (Plasmodium falciparum)

ctsf [lysosomal lumen] (Danio rerio)

ctsf [lysosomal lumen] (Xenopus tropicalis)

CtsF [lysosomal lumen] (Drosophila melanogaster)

tag-196 [lysosomal lumen] (Caenorhabditis elegans)

Ctsf [lysosomal lumen] (Mus musculus)

Ctsf [lysosomal lumen] (Rattus norvegicus)

Cross References

ZINC - World Drugs

CATF_HUMAN

Guide to Pharmacology - Targets

2347

ENSEMBL

ENST00000310325, ENSP00000310832

OpenTargets

ENSG00000174080

ZINC - FDA approved

CATF_HUMAN

ZINC - Substances

CATF_HUMAN

ZINC target

Q9UBX1

PRO

Q9UBX1

PDB

1M6D

ZINC - Investigational

CATF_HUMAN

HPA

ENSG00000174080-CTSF

Pharos - Targets

Q9UBX1

Orphanet

CTSF

ZINC - Predictions - Purchasable

CATF_HUMAN

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P59665 DEFA1	9	DEFA1(20-94) [Golgi lumen] (R-HSA-1467282) DEFA1(66-94) [Golgi lumen] (R-HSA-975663) DEFA1(20-65) [Golgi lumen] (R-HSA-8864970) DEFA1(1-94) [Golgi lumen] (R-HSA-1467215) DEFA1(66-94) [extracellular region] (R-HSA-1461998) DEFA1(66-94) [azurophil granule lumen] (R-HSA-1470038) DEFA1(65-94) [extracellular region] (R-HSA-1462022) omega-N-(ADP-ribosyl)-L-arginine-DEFA1(65-94) [extracellular region] (R-HSA-1972397) DEFA1(65-94) [azurophil granule lumen] (R-HSA-1470053)	0.527	2

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