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CTSL1(114-288)
Stable Identifier
R-HSA-1181225
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Synonyms
Cathepsin L1, CTSL1, CATL1_HUMAN
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX1 (Homo sapiens)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes (Homo sapiens)
SERPINB13 binds cathepsin L (Homo sapiens)
Cathepsin L [lysosomal lumen] (Homo sapiens)
CTSL1(114-288) [lysosomal lumen] (Homo sapiens)
SERPINB13:cathepsin L [lysosomal lumen] (Homo sapiens)
Cathepsin L [lysosomal lumen] (Homo sapiens)
CTSL1(114-288) [lysosomal lumen] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Cleavage of lip22 to lip10 (Homo sapiens)
Cathepsin [lysosomal lumen] (Homo sapiens)
CTSL1(114-288) [lysosomal lumen] (Homo sapiens)
Generation of CLIP from lip10 (Homo sapiens)
Cathepsin [lysosomal lumen] (Homo sapiens)
CTSL1(114-288) [lysosomal lumen] (Homo sapiens)
MHC class II antigen processing (Homo sapiens)
Cathepsin [lysosomal lumen] (Homo sapiens)
CTSL1(114-288) [lysosomal lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P07711 CTSL
Gene Names
CTSL, CTSL1
Chain
signal peptide:1-17, propeptide:18-113, chain:114-288, propeptide:289-291, chain:292-333
Reference Genes
BioGPS Gene:1514 CTSL
CTD Gene:1514 CTSL
dbSNP Gene:1514 CTSL
ENSEMBL:ENSG00000135047 CTSL
HGNC:2537 CTSL
KEGG Gene (Homo sapiens):CTSL CTSL
KEGG Gene (Homo sapiens):hsa:1514 CTSL
Monarch:1514 CTSL
NCBI Gene:1514 CTSL
OMIM:116880 CTSL
UCSC:P07711 CTSL
Reference Transcript
RefSeq:NM_001257972.1 CTSL
RefSeq:NM_145918.2 CTSL
RefSeq:XM_005251716.3 CTSL
RefSeq:NM_001257971.1 CTSL
RefSeq:NM_001912.4 CTSL
Other Identifiers
0003170047
0003990021
11725332_a_at
1514
17086540
1CJL
1CS8
1ICF
1MHW
202087_s_at
2NQD
2VHS
2XU1
2XU3
2XU4
2XU5
2YJ2
2YJ8
2YJ9
2YJB
2YJC
3178148
3178149
3178150
3178151
3178152
3178162
3178163
3178164
3178165
3178168
3178170
3178171
3178174
3178177
3178179
3178180
3178184
3287329
3287613
3288117
3288119
3289420
3297461
3299180
37391_at
3BC3
3H89
3H8B
3H8C
3HHA
3HWN
3IV2
3K24
3KSE
3OF8
3OF9
459
4AXL
4AXM
5F02
5I4H
5MAE
5MAJ
5MQY
8156228
A0A024R276
A_23_P94533
CAB000459
CCDS6675
CTSL
CTSL-201
CTSL-203
ENSG00000135047
ENSP00000345344
ENSP00000365061
ENST00000340342
ENST00000343150
EntrezGene:1514
g4503154_3p_a_at
GE63282
GO:0001968
GO:0002224
GO:0002250
GO:0004197
GO:0004252
GO:0005515
GO:0005518
GO:0005576
GO:0005615
GO:0005634
GO:0005764
GO:0006508
GO:0008233
GO:0008234
GO:0016787
GO:0019882
GO:0019886
GO:0022617
GO:0030574
GO:0036021
GO:0042393
GO:0043202
GO:0043394
GO:0045616
GO:0051603
GO:0070062
GO:0071888
GO:0097067
GO:0097655
HGNC:2537
Hs.731507
ILMN_1694757
ILMN_1812995
ILMN_2374036
MIM:116880
NM_001257971
NM_001257972
NM_001257973
NM_001912
NM_145918
NP_001244900
NP_001244901
NP_001244902
NP_001903
NP_666023
PF00112
PF08246
PH_hs_0030125
PR00705
SM00645
SM00848
TC09000400.hg
TC09002062.hg
uc004aph.4
uc004api.4
UPI000004CAA2
X12451_at
XM_005251716
XM_011518263
XM_017014293
XP_005251773
XP_011516565
XP_016869782
Participant Of
hasCandidate
Cathepsin [lysosomal lumen]
hasMember
Cathepsin [lysosomal lumen]
Cathepsin L [lysosomal lumen]
Other forms of this molecule
CTSL1(114-288) [early endosome lumen]
CTSL(114-288) [extracellular region]
CTSL(292-333) [extracellular region]
CTSL(292-333) [endolysosome lumen]
CTSL(114-288) [endolysosome lumen]
Inferred To
Homologues of CTSL1(114-288) [lysosomal lumen] (Caenorhabditis elegans)
Homologues of CTSL1(114-288) [lysosomal lumen] (Danio rerio)
Homologues of CTSL1(114-288) [lysosomal lumen] (Dictyostelium discoideum)
Homologues of CTSL1(114-288) [lysosomal lumen] (Mus musculus)
Homologues of CTSL1(114-288) [lysosomal lumen] (Rattus norvegicus)
CTSL1(114-288) [lysosomal lumen] (Bos taurus)
CTSL1(114-288) [lysosomal lumen] (Caenorhabditis elegans)
CTSL1(114-288) [lysosomal lumen] (Canis familiaris)
CTSL1(114-288) [lysosomal lumen] (Danio rerio)
CTSL1(114-288) [lysosomal lumen] (Dictyostelium discoideum)
CTSL1(114-288) [lysosomal lumen] (Drosophila melanogaster)
CTSL1(114-288) [lysosomal lumen] (Gallus gallus)
CTSL1(114-288) [lysosomal lumen] (Mus musculus)
CTSL1(114-288) [lysosomal lumen] (Rattus norvegicus)
CTSL1(114-288) [lysosomal lumen] (Sus scrofa)
CTSL1(114-288) [lysosomal lumen] (Taeniopygia guttata)
CTSL1(114-288) [lysosomal lumen] (Xenopus tropicalis)
Cross References
RefSeq
XP_005251773.1
,
NP_666023.1
,
NP_001903.1
,
NP_001244901.1
,
NP_001244900.1
Brenda
3.4.22.15
ZINC - World Drugs
CATL1_HUMAN
ZINC - FDA approved
CATL1_HUMAN
ZINC - Substances
CATL1_HUMAN
ZINC - Biogenic
CATL1_HUMAN
ZINC target
P07711
PRO
P07711
PDB
3H89
,
3H8B
,
1CJL
,
3H8C
,
3HHA
,
3HWN
,
1CS8
,
3IV2
,
1ICF
,
5MAE
,
2YJB
,
5MAJ
,
2YJC
,
5MQY
,
3BC3
,
4AXM
,
2XU5
,
4AXL
,
2XU4
,
2XU3
,
2XU1
,
3OF9
,
2VHS
,
3OF8
,
2NQD
,
3KSE
,
1MHW
,
3K24
,
2YJ9
,
5I4H
,
5F02
,
2YJ8
,
2YJ2
ZINC - Metabolites
CATL1_HUMAN
GeneCards
P07711
DOCK Blaster
2YJC
,
1MHW
,
4AXL
,
4AXM
,
2XU1
,
5MQY
,
2XU3
,
2XU4
,
2XU5
,
2VHS
,
1ICF
,
1CS8
,
3BC3
,
3H8C
,
2YJB
,
3HHA
,
2YJ8
,
2YJ9
,
2YJ2
,
3IV2
,
2NQD
,
1CJL
,
5MAE
,
3H89
,
3H8B
,
5MAJ
,
5I4H
,
5F02
,
3K24
,
3OF9
,
3OF8
,
3HWN
,
3KSE
ZINC - Predictions - Purchasable
CATL1_HUMAN
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