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ACVR2A,B [plasma membrane]
Stable Identifier
R-HSA-1181136
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Activin receptor type IIA,IIB
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Signaling by NODAL (Homo sapiens)
Phosphorylation of R-SMAD2/3 by NODAL receptor (Homo sapiens)
NODAL:p-NODAL Receptor [plasma membrane] (Homo sapiens)
p-Nodal Receptor [plasma membrane] (Homo sapiens)
p-ACVR1B:ACVR2:EGF-CFC [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
Regulation of signaling by NODAL (Homo sapiens)
LEFTY binds the EGF-CFC coreceptor in the NODAL receptor (Homo sapiens)
LEFTY1,2:NODAL Receptor [plasma membrane] (Homo sapiens)
NODAL Receptor [plasma membrane] (Homo sapiens)
ACVR1B:ACVR2A,B:EGF-CFC [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
NODAL Receptor [plasma membrane] (Homo sapiens)
ACVR1B:ACVR2A,B:EGF-CFC [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
The NODAL Receptor binds NODAL ligands (Homo sapiens)
NODAL Ligand:NODAL Receptor [plasma membrane] (Homo sapiens)
NODAL Receptor [plasma membrane] (Homo sapiens)
ACVR1B:ACVR2A,B:EGF-CFC [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
NODAL Receptor [plasma membrane] (Homo sapiens)
ACVR1B:ACVR2A,B:EGF-CFC [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
Type II Activin Receptor (ActRII/ACVR2) phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in response to NODAL (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
NODAL:ACVR1B:ACVR2A,B:EGF-CFC [plasma membrane] (Homo sapiens)
ACVR1B:ACVR2A,B:EGF-CFC [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
NODAL:p-ACVR1B:ACVR2:EGF-CFC [plasma membrane] (Homo sapiens)
p-ACVR1B:ACVR2:EGF-CFC [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by TGFB family members (Homo sapiens)
Signaling by Activin (Homo sapiens)
ACVR2A/B (ActRIIA/B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
Activin A,AB,B:ACVR2A,B:ACVR1B [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
Activin A,AB,B:ACVR2A,B:p-ACVR1B [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
ACVR2A/B (ActRIIA/B) phosphorylates ACVR1C (ActRIC, ALK7) in response to Activin (Homo sapiens)
Activin AB,B:ACVR2A,B:ACVR1C [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
Activin AB,B:ACVR2A,B:p-ACVR1C [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
Activin A/AB/B binds Activin Receptor ACVR2A/B:ACVR1B (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
Activin A,AB,B:ACVR2A,B:ACVR1B [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
Activin AB/B binds Activin Receptor ACVR2A/B:ACVR1C (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
Activin AB,B:ACVR2A,B:ACVR1C [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
Phosphorylation of SMAD2/3 by Activin:Activin Receptor (Homo sapiens)
Activin:ACVR2A,B:p-ACVR1B,C [plasma membrane] (Homo sapiens)
Activin A,AB,B:ACVR2A,B:p-ACVR1B [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
Activin AB,B:ACVR2A,B:p-ACVR1C [plasma membrane] (Homo sapiens)
ACVR2A,B [plasma membrane] (Homo sapiens)
Participants
members
ACVR2A [plasma membrane] (Homo sapiens)
ACVR2B [plasma membrane] (Homo sapiens)
Participant Of
hasComponent
Activin A,AB,B:ACVR2A,B:ACVR1B [plasma membrane]
Activin A,AB,B:ACVR2A,B:p-ACVR1B [plasma membrane]
Activin AB,B:ACVR2A,B:ACVR1C [plasma membrane]
Activin AB,B:ACVR2A,B:p-ACVR1C [plasma membrane]
ACVR1B:ACVR2A,B:EGF-CFC [plasma membrane]
p-ACVR1B:ACVR2:EGF-CFC [plasma membrane]
input
Activin A/AB/B binds Activin Receptor ACVR2A/B:ACVR1B
Activin AB/B binds Activin Receptor ACVR2A/B:ACVR1C
Inferred To
ACVR2B [plasma membrane] (Bos taurus)
ACVR2A,B [plasma membrane] (Canis familiaris)
ACVR2A,B [plasma membrane] (Danio rerio)
ACVR2A,B [plasma membrane] (Mus musculus)
ACVR2A,B [plasma membrane] (Rattus norvegicus)
ACVR2A,B [plasma membrane] (Xenopus tropicalis)
Ghost homologue of ACVR2A,B [plasma membrane] (Drosophila melanogaster)
ACVR2A [plasma membrane] (Gallus gallus)
ACVR2A [plasma membrane] (Sus scrofa)
daf-4 [plasma membrane] (Caenorhabditis elegans)
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