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Placental lactogen [extracellular region]
Stable Identifier
R-HSA-1172022
Type
Complex
Species
Homo sapiens
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Growth hormone receptor signaling (Homo sapiens)
JAK2 phosphorylation (Homo sapiens)
Activated cytokine-like hormone receptors [plasma membrane] (Homo sapiens)
PRLR ligands:Activated PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
Activated cytokine-like hormone receptors, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
PRLR ligands:Activated PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR ligands:Activated PRLR:JAK2 dimer:SH2B1 beta [plasma membrane] (Homo sapiens)
PRLR ligands:Activated PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
Prolactin receptor signaling (Homo sapiens)
JAK2 phosphorylation (Homo sapiens)
Activated cytokine-like hormone receptors [plasma membrane] (Homo sapiens)
PRLR ligands:Activated PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
Activated cytokine-like hormone receptors, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
PRLR ligands:Activated PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR ligands:Activated PRLR:JAK2 dimer:SH2B1 beta [plasma membrane] (Homo sapiens)
PRLR ligands:Activated PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR activation (Homo sapiens)
PRLR ligands:Activated PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR binds SCF beta-TrCP complex (Homo sapiens)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Homo sapiens)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR binds SHP2 (PTPN11) (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer:SHP2 [plasma membrane] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR binds STAT5 (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2:STAT5 [plasma membrane] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR is phosphorylated at Ser-349 (Homo sapiens)
PRLR ligands:Activated PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR-bound STAT5 is phosphorylated (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer:p-STAT5 [plasma membrane] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2:STAT5 [plasma membrane] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
Prolactin receptor is internalized (Homo sapiens)
PRLR ligands:p-S349- PRLR:JAK2 dimer [endosome lumen] (Homo sapiens)
2xp-S349-PRLR:2xJAK2 [endosome lumen] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Homo sapiens)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
Prolactin receptor ligands bind the prolactin receptor (Homo sapiens)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Homo sapiens)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
SH2B binds JAK2 (Homo sapiens)
PRLR ligands:Activated PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR ligands:Activated PRLR:JAK2 dimer:SH2B1 beta [plasma membrane] (Homo sapiens)
PRLR ligands:Activated PRLR:JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
SHP2 is phosphorylated (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer:SHP2 [plasma membrane] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer:p-SHP2 [plasma membrane] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
Tyrosine phosphorylation of PRLR (Homo sapiens)
PRLR ligands:Activated PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Placental lactogen [extracellular region] (Homo sapiens)
Participants
components
x 2
CSH1 [extracellular region]
(Homo sapiens)
Zn2+ [extracellular region]
Participates
as a member of
Prolactin receptor ligands [extracellular region] (Homo sapiens)
Inferred To
Placental lactogen [extracellular region]
(Bos taurus)
Placental lactogen [extracellular region]
(Canis familiaris)
Placental lactogen [extracellular region]
(Danio rerio)
Placental lactogen [extracellular region]
(Gallus gallus)
Placental lactogen [extracellular region]
(Mus musculus)
Placental lactogen [extracellular region]
(Rattus norvegicus)
Placental lactogen [extracellular region]
(Sus scrofa)
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