CARMA1 is phosphorylated and recruits BCL10 and MALT1 to the plasma membrane to form the CBM complex (Sommer et al. 2005, Tanner et al. 2007). Evidence from T cells (Jurkat cells) indicates that MALT1 and BCL10 oligomerize to activate the IKK complex (Zhou 2004).
Sommer, K, Guo, B, Pomerantz, JL, Bandaranayake, AD, Moreno-Garcia, ME, Ovechkina, YL, Rawlings, DJ
Tanner, MJ, Hanel, W, Gaffen, SL, Lin, X
Zhou, H, Wertz, I, O'Rourke, K, Ultsch, M, Seshagiri, S, Eby, M, Xiao, W, Dixit, VM
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