Reactome | NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol]

NF-kappa-B p50,p65,c-Rel:p-IKB

Stable Identifier

R-HSA-1168588

Type

Set [DefinedSet]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

Participants

members

Participant Of

input

SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB

hasComponent

NF-kappaB:p-IkB:SCF-betaTrCP [cytosol]

output

Activated IKK phosphorylates I-kappaB

Inferred To

NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Bos taurus)

NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Canis familiaris)

NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Danio rerio)

NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Drosophila melanogaster)

NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Gallus gallus)

NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Mus musculus)

NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Rattus norvegicus)

NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Sus scrofa)

NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Taeniopygia guttata)

NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Xenopus tropicalis)

© 2018 Reactome