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PLG(20-810) [platelet alpha granule lumen]
Stable Identifier
R-HSA-114647
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
platelet alpha granule lumen
Synonyms
Plasminogen precursor , Angiostatin
Icon
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Exocytosis of platelet alpha granule contents (Homo sapiens)
Platelet alpha granule contents [platelet alpha granule lumen] (Homo sapiens)
PLG(20-810) [platelet alpha granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P00747 PLG
Gene Names
PLG
Chain
signal peptide:1-19, chain:20-810, chain:20-580, peptide:20-97, chain:79-466, chain:98-580, chain:581-810
Reference Genes
BioGPS Gene:5340 PLG
COSMIC (genes):PLG PLG
CTD Gene:5340 PLG
dbSNP Gene:5340 PLG
ENSEMBL:ENSG00000122194 PLG
HGNC:9071 PLG
KEGG:hsa:5340 PLG
Monarch:5340 PLG
NCBI Gene:5340 PLG
OMIM:173350 PLG
UCSC:P00747 PLG
Reference Transcript
RefSeq:NM_000301.3 PLG
Other Identifiers
11720476_a_at
11720477_a_at
11746278_a_at
11757403_x_at
11764270_s_at
1558603_at
17014459
205871_at
209977_PM_at
209977_at
209978_PM_s_at
209978_s_at
214415_PM_at
214415_at
230931_PM_at
230931_at
2492660
2492661
2492663
2492664
2492665
2492671
2492672
2492673
2492678
2492680
2492681
2492682
2492684
2498398
2498404
2498405
2498408
2498409
2498411
2563049
2563051
2563054
2563058
2563059
2563060
2563065
2563067
2563068
2569429
2934684
2934685
2934686
2934687
2934688
2934689
2934690
2934691
2934692
2934695
2934696
2934697
2934698
2934699
2934701
2934706
2934708
2934709
2934710
2934712
2934713
2934714
2934718
2934720
2934721
2934722
2934723
2934724
2934725
2934726
2934727
2934729
2934730
2934731
2934732
2934733
2934734
2934735
2934736
2934737
2934738
2934739
2934740
2982686
2982687
2982690
2982692
2982734
2982744
2982787
36646_at
5340
8043367
8053602
8123259
A_14_P116814
A_23_P30693
A_24_P240487
A_32_P206123
GE59666
GO:0002020
GO:0002376
GO:0003824
GO:0004175
GO:0004252
GO:0005102
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0006508
GO:0007596
GO:0008236
GO:0008285
GO:0009897
GO:0009986
GO:0010812
GO:0016787
GO:0019899
GO:0019900
GO:0019904
GO:0022414
GO:0022617
GO:0023052
GO:0030154
GO:0030198
GO:0030312
GO:0031012
GO:0031093
GO:0034185
GO:0042246
GO:0042730
GO:0043226
GO:0043536
GO:0045445
GO:0046716
GO:0048771
GO:0048856
GO:0048870
GO:0051087
GO:0051702
GO:0051918
GO:0051919
GO:0060707
GO:0060716
GO:0062023
GO:0070062
GO:0071674
GO:0072562
GO:0098685
GO:0098978
GO:0099183
GO:0140096
GO:1990405
GO:2000048
HMNXSV003003655
HMNXSV003037708
Hs.262869.1.S1_3p_at
Hs.81086.1.A1_3p_at
Hs2.391855.1.S1_3p_at
ILMN_1663802
ILMN_1698587
ILMN_1714446
M34276_at
M86873_s_at
PH_hs_0022570
TC02000652.hg
TC02003471.hg
TC06001158.hg
g13529238_3p_at
g190025_3p_at
Participates
as a member of
Platelet alpha granule contents [platelet alpha granule lumen] (Homo sapiens)
Other forms of this molecule
PLG(581-810) [extracellular region]
PLG(20-580) [extracellular region]
PLG(1-810) [extracellular region]
PLG(20-810) [extracellular region]
PLG(20-810) [plasma membrane]
Inferred To
PLG [platelet alpha granule lumen]
(Canis familiaris)
PLG [platelet alpha granule lumen]
(Gallus gallus)
Plg [platelet alpha granule lumen]
(Mus musculus)
Plg [platelet alpha granule lumen]
(Rattus norvegicus)
PLG(20-810) [platelet alpha granule lumen]
(Bos taurus)
PLG(20-810) [platelet alpha granule lumen]
(Caenorhabditis elegans)
PLG(20-810) [platelet alpha granule lumen]
(Sus scrofa)
PLG(20-810) [platelet alpha granule lumen]
(Xenopus tropicalis)
Cross References
RefSeq
NP_000292.1
ZINC - World Drugs
PLMN_HUMAN
Guide to Pharmacology - Targets
2394
OpenTargets
ENSG00000122194
ENSEMBL
ENSP00000308938
,
ENST00000308192
ZINC - FDA approved
PLMN_HUMAN
ZINC - Substances
PLMN_HUMAN
ZINC - Biogenic
PLMN_HUMAN
ZINC target
P00747
PRO
P00747
GlyGen
P00747
PDB
1PMK
,
1CEB
,
1RJX
,
1CEA
,
1PK4
,
1L4D
,
1QRZ
,
5UGD
,
2L0S
,
1B2I
,
6D3Z
,
8F7V
,
6D3Y
,
6Q1U
,
1PKR
,
2PK4
,
1L4Z
,
6UZ5
,
7UAH
,
2KNF
,
7E50
,
6D40
,
6OG4
,
3UIR
,
4CIK
,
1KI0
,
1KRN
,
6D3X
,
8F7U
,
4DUU
,
1BUI
,
1HPJ
,
1HPK
,
5UGG
,
8UQ6
,
1DDJ
,
4A5T
,
1I5K
,
2DOH
,
4DCB
,
2DOI
,
5HPG
,
1BML
,
6UZ4
,
7THS
,
6OQK
,
4DUR
,
6OQJ
ZINC - Investigational
PLMN_HUMAN
ZINC - Metabolites
PLMN_HUMAN
HPA
ENSG00000122194-PLG
Pharos - Targets
P00747
Orphanet
PLG
ZINC - Predictions - Purchasable
PLMN_HUMAN
HMDB Protein
HMDBP01984
Interactors (19)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P75391 ODPB
0.83
11
UniProt:P75392 ODP2
0.656
5
UniProt:P75390 ODPA
0.656
5
UniProt:P28300-PRO_0000018520 LOX
0.558
2
UniProt:Q6V4L4 Q6V4L4
0.558
2
UniProt:Q6V4L5 Q6V4L5
0.558
2
UniProt:Q6V4L1 Q6V4L1
0.558
2
UniProt:Q99SU7 SAK
0.558
7
UniProt:Q6V4L9 Q6V4L9
0.558
2
UniProt:Q3SYB3 FX4L6
0.556
3
IntAct:EBI-25850457 CCSB
0.556
3
UniProt:Q8N4S9 MALD2
0.544
2
UniProt:P27348 YWHAQ
1
YWHAQ [cytosol]
(R-HSA-1445116)
0.527
2
UniProt:P00830 ATP2
5
ATP5F1B [mitochondrial matrix]
(R-SCE-164576)
ATP2 precursor [cytosol]
(R-SCE-1252203)
ATP2 precursor [mitochondrial intermembrane space]
(R-SCE-1252202)
ATP2 precursor [mitochondrial inner membrane]
(R-SCE-1252057)
ATP2 [mitochondrial inner membrane]
(R-SCE-1267966)
0.524
2
UniProt:P21306 ATP5E
0.524
2
UniProt:Q12165 ATPD
0.524
2
UniProt:P38077
1
ATP3 [mitochondrial matrix]
(R-SCE-164577)
0.524
2
UniProt:P75393 DLDH
0.524
3
UniProt:P07251 ATP1
3
ATP5F1A [mitochondrial matrix]
(R-SCE-164575)
ATP1 precursor [cytosol]
(R-SCE-1252120)
ATP1 precursor [mitochondrial intermembrane space]
(R-SCE-1252145)
0.524
2
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