Adhesion of integrin alphaIIbbeta3 to fibrin network

Stable Identifier
R-HSA-114560
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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Adhesion of integrin alphaIIbbeta3 to fibrin network
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the beginning of this reaction, 1 molecule of 'fibrin multimer', and 1 molecule of 'Alpha IIb Beta 3 Integrin' are present. At the end of this reaction, 1 molecule of 'Integrin alpha IIb beta 3:Fibrin complex' is present.


Literature References
PubMed ID Title Journal Year
10605720 Signaling through platelet integrin alpha IIb beta 3: inside-out, outside-in, and sideways

Shattil, SJ

Thromb Haemost 1999
Participants
Input
Output
Participates
as an event of
Orthologous Events
Adhesion of integrin alphaIIbbeta3 to fibrin network (Gallus gallus)
Adhesion of integrin alphaIIbbeta3 to fibrin network (Mus musculus)
Adhesion of integrin alphaIIbbeta3 to fibrin network (Rattus norvegicus)
Adhesion of integrin alphaIIbbeta3 to fibrin network (Sus scrofa)
Authored
Geiger, B  (2008-05-07)
Horwitz, AR  (2008-05-07)
Reviewed
Humphries, MJ  (2008-05-07)
Yamada, KM  (2008-05-07)
Hynes, R  (2008-05-07)
Created
Farndale, R  (2004-09-25)
Pace, NP  (2004-09-25)
de Bono, B  (2004-09-25)
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