Release of Cytochrome c from mitochondria

Stable Identifier
R-HSA-114284
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Permeabilization of the outer mitochondrial membrane by pro-apoptotic BCL2 family proteins, such as BAK and BAX, allows cytochrome c eflux from the mitochondrial intermembrane space into the cytosol (Arnoult et al. 2003).

Literature References
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This event is regulated
Orthologous Events
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Created