Translocation of activated BAX to the mitochondria

Stable Identifier
Reaction [transition]
Homo sapiens
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Activated BAX integrates in the outer mitochondrial membrane (Eskes et al. 2000, Antonsson et al. 2001, Bellosillo et al. 2002, Yi et al. 2003).
Literature References
PubMed ID Title Journal Year
11136736 Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells.

Martinou, JC, Antonsson, B, Montessuit, S, Sanchez, B

J Biol Chem 2001
12624108 Inhibition of Bid-induced apoptosis by Bcl-2. tBid insertion, Bax translocation, and Bax/Bak oligomerization suppressed

Dong, Z, Yin, XM, Yi, X

J Biol Chem 2003
10629050 Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

Desagher, S, Eskes, R, Martinou, JC, Antonsson, B

Mol Cell Biol 2000
12176904 Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia.

Villamor, N, Bellosillo, B, Colomer, D, Montserrat, E, Marcé, S, López-Guillermo, A, Campo, E, Bosch, F

Blood 2002
Event Information
Orthologous Events
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