During S phase of the cell cycle, RB1 is dephosphorylated by the PP2A protein phosphatase complex. Unphosphorylated RB1 associates with DNA damage sites in S phase, preventing initiation of DNA replication from these sites (Knudsen et al. 2000, Avni et al. 2003).
Livingston, DM, Ganesan, S, Scully, R, Hofmann, F, ElShamy, WM, Yang, H, Martelli, F, Avni, D
Capogrossi, MC, Martelli, F, Fasanaro, P, Di Stefano, V, Romani, S, Magenta, A
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