Recruitment of elongation factors to form elongation complex

Stable Identifier
R-HSA-112379
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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At the beginning of this reaction, 1 molecule of 'FACT complex', 1 molecule of 'Elongin Complex', 1 molecule of 'Early elongation complex with hyperphosphorylated Pol II CTD', 1 molecule of 'TFIIH', 1 molecule of 'RNA polymerase II elongation factor ELL', and 1 molecule of 'TFIIS protein' are present. At the end of this reaction, 1 molecule of 'Elongation complex' is present.

This reaction takes place in the 'nucleus'.

Literature References
PubMed ID Title Journal Year
19952111 DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation

Chen, Y, Yamaguchi, Y, Tsugeno, Y, Yamamoto, J, Yamada, T, Nakamura, M, Hisatake, K, Handa, H

Genes Dev. 2009
17234882 The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export

Yoh, SM, Cho, H, Pickle, L, Evans, RM, Jones, KA

Genes Dev. 2007
26659056 RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II

Yu, M, Yang, W, Ni, T, Tang, Z, Nakadai, T, Zhu, J, Roeder, RG

Science 2015
12676794 The RNA polymerase II elongation complex.

Shilatifard, A, Conaway, RC, Conaway, JW

Annu Rev Biochem 2003
Participants
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Orthologous Events
Created