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G alpha (i) [plasma membrane]
Stable Identifier
R-HSA-112270
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Signal amplification (Homo sapiens)
ADP signalling through P2Y purinoceptor 12 (Homo sapiens)
Activated P2Y purinoceptor 12 binds G-protein Gi (Homo sapiens)
ADP:P2RY12:G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Dissociation of the P2Y purinoceptor 12:Gi complex (Homo sapiens)
ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Gi activation by P2Y purinoceptor 12 (Homo sapiens)
ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
ADP:P2RY12:G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
GABA receptor activation (Homo sapiens)
GABA B receptor activation (Homo sapiens)
Activation of GABAB receptors (Homo sapiens)
Adenylate cyclase inhibitory pathway (Homo sapiens)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Adenylate cyclase increases the GTPase activity of Gi alpha (Homo sapiens)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Dissociation of the Gi alpha:G olf complex (Homo sapiens)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (i) inhibits adenylate cyclase (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Active G alpha (i)–i1/i2/i3 binds RGS proteins (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (i):GTP:RGS [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (i) auto-inactivates by hydrolysing GTP to GDP (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (i) inhibits adenylate cyclase (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (i):GTP binds SRC (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (i):GTP:SRC-1 [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Homo sapiens)
G alpha (i):GDP:RGS [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Homo sapiens)
G alpha (i):GDP:RGS [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (i):GTP:RGS [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (i):GTP:SRC-1 [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G protein alpha (i):GTP:p-Y419-SRC [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G protein alpha (i):GTP:p-Y419-SRC [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Inactive G alpha (i) reassociates with G beta:gamma (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Opioid Signalling (Homo sapiens)
G-protein mediated events (Homo sapiens)
Adenylate cyclase inhibitory pathway (Homo sapiens)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Adenylate cyclase increases the GTPase activity of Gi alpha (Homo sapiens)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Dissociation of the Gi alpha:G olf complex (Homo sapiens)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (i) inhibits adenylate cyclase (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
GPER1 signaling (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G alpha (z) signalling events (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Extra-nuclear estrogen signaling (Homo sapiens)
G-proteins dissociate from plasma-membrane estrogen receptors (Homo sapiens)
ESTG:ESRs:STRN:heterotrimeric G(i) protein [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG (Homo sapiens)
ESTG:ESRs:STRN:heterotrimeric G(i) protein [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Membrane estrogen receptors bind SRC (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i) [plasma membrane] (Homo sapiens)
Participants
members
GNAI3 [plasma membrane]
(Homo sapiens)
GNAI1 [plasma membrane]
(Homo sapiens)
GNAI2 [plasma membrane]
(Homo sapiens)
GNAT3 [plasma membrane]
(Homo sapiens)
Participates
as a component of
G alpha (i):GDP:RGS [plasma membrane] (Homo sapiens)
G-protein alpha (i):GDP [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
Inferred To
G alpha (i) [plasma membrane]
(Bos taurus)
G alpha (i) [plasma membrane]
(Caenorhabditis elegans)
G alpha (i) [plasma membrane]
(Canis familiaris)
G alpha (i) [plasma membrane]
(Danio rerio)
G alpha (i) [plasma membrane]
(Dictyostelium discoideum)
G alpha (i) [plasma membrane]
(Gallus gallus)
G alpha (i) [plasma membrane]
(Mus musculus)
G alpha (i) [plasma membrane]
(Rattus norvegicus)
G alpha (i) [plasma membrane]
(Saccharomyces cerevisiae)
G alpha (i) [plasma membrane]
(Schizosaccharomyces pombe)
G alpha (i) [plasma membrane]
(Sus scrofa)
G alpha (i) [plasma membrane]
(Xenopus tropicalis)
GNAI3 [plasma membrane]
(Drosophila melanogaster)
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