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G-protein mediated events
Stable Identifier
R-HSA-112040
Type
Pathway
Species
Homo sapiens
Compartment
plasma membrane
,
endoplasmic reticulum membrane
,
endoplasmic reticulum lumen
,
nucleoplasm
,
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Opioid Signalling (Homo sapiens)
G-protein mediated events (Homo sapiens)
General
SBML
|
BioPAX
Level 2
Level 3
|
PDF
SVG
|
PNG
Low
Medium
High
|
PPTX
|
SBGN
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When dissociated Galpha-GTP and Gbeta-gamma can activate or inhibit different signalling cascades and effector proteins. The precise pathways depends on the identity of the alpha and beta/gamma subtypes.
Literature References
PubMed ID
Title
Journal
Year
9218123
G proteins and opioid receptor-mediated signalling
Pasternak, GW
,
Standifer, KM
Cell Signal
1997
9422713
The many faces of G protein signaling
Hamm, HE
J Biol Chem
1998
Participants
Events
PLC beta mediated events
(Homo sapiens)
Adenylate cyclase activating pathway
(Homo sapiens)
Adenylate cyclase inhibitory pathway
(Homo sapiens)
Participates
as an event of
Opioid Signalling (Homo sapiens)
Orthologous Events
G-protein mediated events (Bos taurus)
G-protein mediated events (Caenorhabditis elegans)
G-protein mediated events (Canis familiaris)
G-protein mediated events (Danio rerio)
G-protein mediated events (Dictyostelium discoideum)
G-protein mediated events (Drosophila melanogaster)
G-protein mediated events (Gallus gallus)
G-protein mediated events (Mus musculus)
G-protein mediated events (Plasmodium falciparum)
G-protein mediated events (Rattus norvegicus)
G-protein mediated events (Saccharomyces cerevisiae)
G-protein mediated events (Schizosaccharomyces pombe)
G-protein mediated events (Sus scrofa)
G-protein mediated events (Xenopus tropicalis)
Authored
Jassal, B (2004-03-31)
Le Novere, N (2004-03-31)
Reviewed
Castagnoli, L (2008-11-06)
Created
Schmidt, EE (2004-04-06)
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